Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PL(pro)

The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has called for an urgent need for dedicated antiviral therapeutics. Metal complexes are commonly underrepresented in compound libraries that are used for screening in drug discovery campaigns, however, there is gro...

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Detalles Bibliográficos
Autores principales: Gil‐Moles, Maria, Türck, Sebastian, Basu, Uttara, Pettenuzzo, Andrea, Bhattacharya, Saurav, Rajan, Ananthu, Ma, Xiang, Büssing, Rolf, Wölker, Jessica, Burmeister, Hilke, Hoffmeister, Henrik, Schneeberg, Pia, Prause, Andre, Lippmann, Petra, Kusi‐Nimarko, Josephine, Hassell‐Hart, Storm, McGown, Andrew, Guest, Daniel, Lin, Yan, Notaro, Anna, Vinck, Robin, Karges, Johannes, Cariou, Kevin, Peng, Kun, Qin, Xue, Wang, Xing, Skiba, Joanna, Szczupak, Łukasz, Kowalski, Konrad, Schatzschneider, Ulrich, Hemmert, Catherine, Gornitzka, Heinz, Milaeva, Elena R., Nazarov, Alexey A., Gasser, Gilles, Spencer, John, Ronconi, Luca, Kortz, Ulrich, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653295/
https://www.ncbi.nlm.nih.gov/pubmed/34714566
http://dx.doi.org/10.1002/chem.202103258

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