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A network SIRX model for the spreading of COVID-19

Infectious diseases, such as the current COVID-19, have a huge economic and societal impact. The ability to model its transmission characteristics is critical to minimize its impact. In fact, predicting how fast an infection is spreading could be a major factor in deciding on the severity, extent an...

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Autores principales: Dimou, Argyris, Maragakis, Michael, Argyrakis, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653413/
https://www.ncbi.nlm.nih.gov/pubmed/34898823
http://dx.doi.org/10.1016/j.physa.2021.126746
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author Dimou, Argyris
Maragakis, Michael
Argyrakis, Panos
author_facet Dimou, Argyris
Maragakis, Michael
Argyrakis, Panos
author_sort Dimou, Argyris
collection PubMed
description Infectious diseases, such as the current COVID-19, have a huge economic and societal impact. The ability to model its transmission characteristics is critical to minimize its impact. In fact, predicting how fast an infection is spreading could be a major factor in deciding on the severity, extent and strictness of the applied mitigation measures, such as the recent lockdowns. Even though modelling epidemics is a well studied subject, usually models do not include quarantine or other social measures, such as those imposed in the recent pandemic. The current work builds upon a recent paper by Maier and Brockmann (2020), where a compartmental SIRX model was implemented. That model included social or individual behavioural changes during quarantine, by introducing state [Formula: see text] , in which symptomatic quarantined individuals are not transmitting the infection anymore, and described well the transmission in the initial stages of the infection. The results of the model were applied to real data from several provinces in China, quite successfully. In our approach we use a Monte-Carlo simulation model on networks. Individuals are network nodes and the links are their contacts. We use a spreading mechanism from the initially infected nodes to their nearest neighbours, as has been done previously. Initially, we find the values of the rate constants (parameters) the same way as in Maier and Brockmann (2020) for the confirmed cases of a country, on a daily basis, as given by the Johns Hopkins University. We then use different types of networks (random Erdős–Rényi, Small World, and Barabási–Albert Scale-Free) with various characteristics in an effort to find the best fit with the real data for the same geographical regions as reported in Maier and Brockmann (2020). Our simulations show that the best fit comes with the Erdős–Rényi random networks. We then apply this method to several other countries, both for large-size countries, and small size ones. In all cases investigated we find the same result, i.e. best agreement for the evolution of the pandemic with time is for the Erdős–Rényi networks. Furthermore, our results indicate that the best fit occurs for a random network with an average degree of the order of [Formula: see text] 10–25, for all countries tested. Scale Free and Small World networks fail to fit the real data convincingly.
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spelling pubmed-86534132021-12-08 A network SIRX model for the spreading of COVID-19 Dimou, Argyris Maragakis, Michael Argyrakis, Panos Physica A Article Infectious diseases, such as the current COVID-19, have a huge economic and societal impact. The ability to model its transmission characteristics is critical to minimize its impact. In fact, predicting how fast an infection is spreading could be a major factor in deciding on the severity, extent and strictness of the applied mitigation measures, such as the recent lockdowns. Even though modelling epidemics is a well studied subject, usually models do not include quarantine or other social measures, such as those imposed in the recent pandemic. The current work builds upon a recent paper by Maier and Brockmann (2020), where a compartmental SIRX model was implemented. That model included social or individual behavioural changes during quarantine, by introducing state [Formula: see text] , in which symptomatic quarantined individuals are not transmitting the infection anymore, and described well the transmission in the initial stages of the infection. The results of the model were applied to real data from several provinces in China, quite successfully. In our approach we use a Monte-Carlo simulation model on networks. Individuals are network nodes and the links are their contacts. We use a spreading mechanism from the initially infected nodes to their nearest neighbours, as has been done previously. Initially, we find the values of the rate constants (parameters) the same way as in Maier and Brockmann (2020) for the confirmed cases of a country, on a daily basis, as given by the Johns Hopkins University. We then use different types of networks (random Erdős–Rényi, Small World, and Barabási–Albert Scale-Free) with various characteristics in an effort to find the best fit with the real data for the same geographical regions as reported in Maier and Brockmann (2020). Our simulations show that the best fit comes with the Erdős–Rényi random networks. We then apply this method to several other countries, both for large-size countries, and small size ones. In all cases investigated we find the same result, i.e. best agreement for the evolution of the pandemic with time is for the Erdős–Rényi networks. Furthermore, our results indicate that the best fit occurs for a random network with an average degree of the order of [Formula: see text] 10–25, for all countries tested. Scale Free and Small World networks fail to fit the real data convincingly. Elsevier B.V. 2022-03-15 2021-12-08 /pmc/articles/PMC8653413/ /pubmed/34898823 http://dx.doi.org/10.1016/j.physa.2021.126746 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Dimou, Argyris
Maragakis, Michael
Argyrakis, Panos
A network SIRX model for the spreading of COVID-19
title A network SIRX model for the spreading of COVID-19
title_full A network SIRX model for the spreading of COVID-19
title_fullStr A network SIRX model for the spreading of COVID-19
title_full_unstemmed A network SIRX model for the spreading of COVID-19
title_short A network SIRX model for the spreading of COVID-19
title_sort network sirx model for the spreading of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653413/
https://www.ncbi.nlm.nih.gov/pubmed/34898823
http://dx.doi.org/10.1016/j.physa.2021.126746
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