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An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report
A breast mass in women often presents a diagnostic challenge due to the diversity in the diagnosis. We herein report a rare variant of breast carcinoma, an invasive apocrine carcinoma (AC), in an elderly woman where the breast mass clinically mimicked phyllodes tumour. Immunohistochemistry (IHC) sho...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653463/ https://www.ncbi.nlm.nih.gov/pubmed/34934704 http://dx.doi.org/10.4103/jfmpc.jfmpc_176_21 |
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author | Singh, Mahendra Pratap Brahmachari, Swagata Arya, Neha |
author_facet | Singh, Mahendra Pratap Brahmachari, Swagata Arya, Neha |
author_sort | Singh, Mahendra Pratap |
collection | PubMed |
description | A breast mass in women often presents a diagnostic challenge due to the diversity in the diagnosis. We herein report a rare variant of breast carcinoma, an invasive apocrine carcinoma (AC), in an elderly woman where the breast mass clinically mimicked phyllodes tumour. Immunohistochemistry (IHC) showed the tumour as triple-negative and also negative for androgen receptor (AR). Gross cystic disease fluid protein (GCDFP-15) was strongly and diffusely positive. It is an exceptional finding. It implies its significance as a diagnostic marker of AC of the breast. The accurate diagnostic criteria of AC are still lacking. Patients with breast lumps offer unique challenges and enormous responsibility to primary and family care physicians. |
format | Online Article Text |
id | pubmed-8653463 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-86534632021-12-20 An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report Singh, Mahendra Pratap Brahmachari, Swagata Arya, Neha J Family Med Prim Care Case Report A breast mass in women often presents a diagnostic challenge due to the diversity in the diagnosis. We herein report a rare variant of breast carcinoma, an invasive apocrine carcinoma (AC), in an elderly woman where the breast mass clinically mimicked phyllodes tumour. Immunohistochemistry (IHC) showed the tumour as triple-negative and also negative for androgen receptor (AR). Gross cystic disease fluid protein (GCDFP-15) was strongly and diffusely positive. It is an exceptional finding. It implies its significance as a diagnostic marker of AC of the breast. The accurate diagnostic criteria of AC are still lacking. Patients with breast lumps offer unique challenges and enormous responsibility to primary and family care physicians. Wolters Kluwer - Medknow 2021-10 2021-11-05 /pmc/articles/PMC8653463/ /pubmed/34934704 http://dx.doi.org/10.4103/jfmpc.jfmpc_176_21 Text en Copyright: © 2021 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Singh, Mahendra Pratap Brahmachari, Swagata Arya, Neha An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report |
title | An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report |
title_full | An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report |
title_fullStr | An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report |
title_full_unstemmed | An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report |
title_short | An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report |
title_sort | elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: a rare case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653463/ https://www.ncbi.nlm.nih.gov/pubmed/34934704 http://dx.doi.org/10.4103/jfmpc.jfmpc_176_21 |
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