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An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report

A breast mass in women often presents a diagnostic challenge due to the diversity in the diagnosis. We herein report a rare variant of breast carcinoma, an invasive apocrine carcinoma (AC), in an elderly woman where the breast mass clinically mimicked phyllodes tumour. Immunohistochemistry (IHC) sho...

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Autores principales: Singh, Mahendra Pratap, Brahmachari, Swagata, Arya, Neha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653463/
https://www.ncbi.nlm.nih.gov/pubmed/34934704
http://dx.doi.org/10.4103/jfmpc.jfmpc_176_21
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author Singh, Mahendra Pratap
Brahmachari, Swagata
Arya, Neha
author_facet Singh, Mahendra Pratap
Brahmachari, Swagata
Arya, Neha
author_sort Singh, Mahendra Pratap
collection PubMed
description A breast mass in women often presents a diagnostic challenge due to the diversity in the diagnosis. We herein report a rare variant of breast carcinoma, an invasive apocrine carcinoma (AC), in an elderly woman where the breast mass clinically mimicked phyllodes tumour. Immunohistochemistry (IHC) showed the tumour as triple-negative and also negative for androgen receptor (AR). Gross cystic disease fluid protein (GCDFP-15) was strongly and diffusely positive. It is an exceptional finding. It implies its significance as a diagnostic marker of AC of the breast. The accurate diagnostic criteria of AC are still lacking. Patients with breast lumps offer unique challenges and enormous responsibility to primary and family care physicians.
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spelling pubmed-86534632021-12-20 An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report Singh, Mahendra Pratap Brahmachari, Swagata Arya, Neha J Family Med Prim Care Case Report A breast mass in women often presents a diagnostic challenge due to the diversity in the diagnosis. We herein report a rare variant of breast carcinoma, an invasive apocrine carcinoma (AC), in an elderly woman where the breast mass clinically mimicked phyllodes tumour. Immunohistochemistry (IHC) showed the tumour as triple-negative and also negative for androgen receptor (AR). Gross cystic disease fluid protein (GCDFP-15) was strongly and diffusely positive. It is an exceptional finding. It implies its significance as a diagnostic marker of AC of the breast. The accurate diagnostic criteria of AC are still lacking. Patients with breast lumps offer unique challenges and enormous responsibility to primary and family care physicians. Wolters Kluwer - Medknow 2021-10 2021-11-05 /pmc/articles/PMC8653463/ /pubmed/34934704 http://dx.doi.org/10.4103/jfmpc.jfmpc_176_21 Text en Copyright: © 2021 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Singh, Mahendra Pratap
Brahmachari, Swagata
Arya, Neha
An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report
title An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report
title_full An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report
title_fullStr An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report
title_full_unstemmed An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report
title_short An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report
title_sort elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653463/
https://www.ncbi.nlm.nih.gov/pubmed/34934704
http://dx.doi.org/10.4103/jfmpc.jfmpc_176_21
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