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Glycyrrhizin mitigates inflammatory bone loss and promotes expression of senescence-protective sirtuins in an aging mouse model of periprosthetic osteolysis

Although periprosthetic osteolysis induced by wear debris particles is significantly elevated in senior (65+ years old) patients, most of the published pre-clinical studies were performed using young (less than three-month old) mice indicating the critical need to employ experimental models of parti...

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Detalles Bibliográficos
Autores principales: Yamada, Chiaki, Ho, Anny, Akkaoui, Juliet, Garcia, Christopher, Duarte, Carolina, Movila, Alexandru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653540/
https://www.ncbi.nlm.nih.gov/pubmed/33770668
http://dx.doi.org/10.1016/j.biopha.2021.111503

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