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Intradiscal injection of monosodium iodoacetate induces intervertebral disc degeneration in an experimental rabbit model
BACKGROUND: Establishing an optimal animal model for intervertebral disc (IVD) degeneration is essential for developing new IVD therapies. The intra-articular injection of monosodium iodoacetate (MIA), which is commonly used in animal models of osteoarthritis, induces cartilage degeneration and prog...
Autores principales: | Sudo, Takao, Akeda, Koji, Kawaguchi, Koki, Hasegawa, Takahiro, Yamada, Junichi, Inoue, Nozomu, Masuda, Koichi, Sudo, Akihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653558/ https://www.ncbi.nlm.nih.gov/pubmed/34876212 http://dx.doi.org/10.1186/s13075-021-02686-6 |
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