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CYP2E1 inhibition and NF_κB Signaling Pathway are Involved in the Protective Molecular Effect of Origanum floribundum against Acetaminophen-induced acute Hepatotoxicity in Rats

The present study aimed to estimate the potential and the molecular mechanism of the hydro-ethanolic extract of O.floribundum against acetaminophen (AC) induced hepatotoxicity. Four groups of female Wistar rats (n=6) was formed to study the hepatoprotective effect of O.floribundum extract against ac...

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Detalles Bibliográficos
Autores principales: Khelfallah, Amina, Aouay, Bakhta, Kebieche, Mohamed, Fetoui, Hamadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653642/
https://www.ncbi.nlm.nih.gov/pubmed/34904010
http://dx.doi.org/10.22037/ijpr.2021.114487.14878