Cargando…

Improved Ocular Bioavailability of Moxifloxacin HCl using PLGA Nanoparticles: Fabrication, Characterization, In-vitro and In-vivo Evaluation

Improving the bioavailability of a drug at the ocular surface presents a profound challenge. Due to ocular physiological barriers, conventional eye drops exhibit poor bioavailability of drugs. Sustained-release nanoparticles may improve the residence time and hence increase absorption of the drug fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Fahim Ullah, Nasir, Fazli, Iqbal, Zafar, Neau, Steven, Khan, Ismail, Hassan, Mohammad, Iqbal, Muhammad, Ullah, Aman, Khan, Sumaira Irum, Sakhi, Mirina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653660/ https://www.ncbi.nlm.nih.gov/pubmed/34904011 http://dx.doi.org/10.22037/ijpr.2021.114478.15054

Ejemplares similares

Effect of polymeric stabilizers on the size and stability of PLGA paclitaxel nanoparticles
por: Sakhi, Mirina, et al.
Publicado: (2023)

Design and Characterization of Paclitaxel-Loaded Polymeric Nanoparticles Decorated With Trastuzumab for the Effective Treatment of Breast Cancer
por: Sakhi, Mirina, et al.
Publicado: (2022)

Tamoxifen-Loaded Eudragit Nanoparticles: Quality by Design Approach for Optimization of Nanoparticles as Delivery System
por: Khattak, Muzna Ali, et al.
Publicado: (2023)

An Improvement of the Efficacy of Moxifloxacin HCl for the Treatment of Bacterial Keratitis by the Formulation of Ocular Mucoadhesive Microspheres
por: Dandagi, Panchaxari Mallappa, et al.
Publicado: (2013)

Fabrication and characterization of glimepiride nanosuspension by ultrasonication-assisted precipitation for improvement of oral bioavailability and in vitro α-glucosidase inhibition
por: Rahim, Haroon, et al.
Publicado: (2019)

Enhancement of dissolution rate of class II drugs (Hydrochlorothiazide); a comparative study of the two novel approaches; solid dispersion and liqui-solid techniques
por: Khan, Amjad, et al.
Publicado: (2015)

Stability indicating HPLC method for the simultaneous determination of moxifloxacin and prednisolone in pharmaceutical formulations
por: Razzaq, Syed Naeem, et al.
Publicado: (2012)

Preparation, Characterization, and Evaluation of Physcion Nanoparticles for Enhanced Oral Bioavailability: An Attempt to Improve Its Antioxidant and Anticancer Potential
por: Khuda, Fazli, et al.
Publicado: (2023)

Self-emulsifying micelles as a drug nanocarrier system for itraconazole oral bioavailability enhancement; in vitro and in vivo assessment
por: Islam, Nayyer, et al.
Publicado: (2023)

Gellan Gum-Based Bilayer Mucoadhesive Films Loaded with Moxifloxacin Hydrochloride and Clove Oil for Possible Treatment of Periodontitis
por: Li, Aiqin, et al.
Publicado: (2021)

In-Vitro and In-Vivo Evaluation of Velpatasvir- Loaded Mesoporous Silica Scaffolds. A Prospective Carrier for Drug Bioavailability Enhancement
por: Mehmood, Yasir, et al.
Publicado: (2020)

COVID-19 pandemic and financial market volatility: A quantile regression approach
por: Ullah, Sabeeh, et al.
Publicado: (2023)

Moxifloxacin HCl-Incorporated Aqueous-Induced Nitrocellulose-Based In Situ Gel for Periodontal Pocket Delivery
por: Senarat, Setthapong, et al.
Publicado: (2023)

Genetic diversity in exotic oat germplasm & resistance against barley yellow dwarf virus
por: Jan, Shazma Firdous, et al.
Publicado: (2020)

Biosynthesized Silver Nanoparticles Using Alnus nitida Leaf Extract as a Potential Antioxidant and Anticancer Agent
por: Khuda, Fazli, et al.
Publicado: (2023)

Formulation Development and Characterization of pH Responsive Polymeric Nano-Pharmaceuticals for Targeted Delivery of Anti-Cancer Drug (Methotrexate)
por: Ullah, Farhad, et al.
Publicado: (2022)

Fabrication and in vivo evaluation of Nelfinavir loaded PLGA nanoparticles for enhancing oral bioavailability and therapeutic effect
por: Venkatesh, D. Nagasamy, et al.
Publicado: (2015)

Preparation and In Vitro/Ex Vivo Evaluation of Moxifloxacin-Loaded PLGA Nanosuspensions for Ophthalmic Application
por: Mudgil, Meetali, et al.
Publicado: (2013)

Electrospun PLGA Membranes with Incorporated Moxifloxacin-Loaded Silica-Based Mesoporous Nanocarriers for Periodontal Regeneration
por: Pouroutzidou, Georgia K., et al.
Publicado: (2022)

Improved Bioavailability of Ebastine through Development of Transfersomal Oral Films
por: Islam, Nayyer, et al.
Publicado: (2021)

Oral bioavailability and pharmacokinetic study of cetrizine HCl in Iranian healthy volunteers
por: Derakhshandeh, K., et al.
Publicado: (2009)

The effect of topical ocular moxifloxacin on conjunctival and nasal mucosal flora
por: Celebi, Ali Riza Cenk, et al.
Publicado: (2021)

Fabrication of Bacterial Cellulose-Curcumin Nanocomposite as a Novel Dressing for Partial Thickness Skin Burn
por: Sajjad, Wasim, et al.
Publicado: (2020)

Development and Evaluation of pH-Responsive Pluronic F 127 Co-Poly- (Acrylic Acid) Biodegradable Nanogels for Topical Delivery of Terbinafine HCL
por: Hassan, Shams ul, et al.
Publicado: (2022)

Preparation, Evaluation and Bioavailability Studies of Eudragit Coated PLGA Nanoparticles for Sustained Release of Eluxadoline for the Treatment of Irritable Bowel Syndrome
por: Anwer, Md. K., et al.
Publicado: (2017)

Fabrication of an Efficient Planar Organic-Silicon Hybrid Solar Cell with a 150 nm Thick Film of PEDOT: PSS
por: Iqbal, Sami, et al.
Publicado: (2019)

Enhancement of Oral Bioavailability of Ibandronate Through Gastroretentive Raft Forming Drug Delivery System: In Vitro and In Vivo Evaluation
por: Hanif, Muhammad, et al.
Publicado: (2020)

Metformin HCl-loaded transethosomal gel; development, characterization, and antidiabetic potential evaluation in the diabetes-induced rat model
por: Nousheen, Kainat, et al.
Publicado: (2023)

Formulation of Aceclofenac Tablets Using Nanosuspension as Granulating Agent: An Attempt to Enhance Dissolution Rate and Oral Bioavailability
por: Rahim, Haroon, et al.
Publicado: (2020)

Design of Topical Moxifloxacin Mucoadhesive Nanoemulsion for the Management of Ocular Bacterial Infections
por: Youssef, Ahmed Adel Ali, et al.
Publicado: (2022)

Analyzing the linkage among CO(2) emissions, economic growth, tourism, and energy consumption in the Asian economies
por: Nosheen, Misbah, et al.
Publicado: (2021)

Attention based parameter estimation and states forecasting of COVID-19 pandemic using modified SIQRD Model()
por: Khan, Junaid Iqbal, et al.
Publicado: (2022)

Composite PLGA–Nanobioceramic Coating on Moxifloxacin-Loaded Akermanite 3D Porous Scaffolds for Bone Tissue Regeneration
por: Pouroutzidou, Georgia K., et al.
Publicado: (2023)

Green synthesis and characterization of copper nanoparticles for investigating their effect on germination and growth of wheat
por: Kausar, Humaira, et al.
Publicado: (2022)

Phytochemical Screening, Antibacterial Activity and Heavy Metal Analysis of Ethnomedicinal Recipes and Their Sources Used Against Infectious Diseases
por: Mahmood, Nasir, et al.
Publicado: (2019)

Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks
por: Subhan, Fazli, et al.
Publicado: (2011)

Physicochemical Characterizations and Pharmacokinetic Evaluation of Pentazocine Solid Lipid Nanoparticles against Inflammatory Pain Model
por: Khan, Zaheer Ullah, et al.
Publicado: (2022)

Fighting adult illiteracy with the help of the environmental print material
por: Iqbal, Tassawar, et al.
Publicado: (2018)

Viscosine as a Potent and Safe Antipyretic Agent Evaluated by Yeast-Induced Pyrexia Model and Molecular Docking Studies
por: Muhammad, Akhtar, et al.
Publicado: (2019)

Bioavailability of l-lysine sulfate relative to l-lysine HCl for growing–finishing pigs
por: Li, Qingyun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_sg60u67bet37157pum35o8e03d