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Development and Validation of four Nitrosamine Impurities Determination Method in Medicines of Valsartan, Losartan, and Irbesartan with HPLC-MS/MS (APCI)

Since 2018, regulation and control of genotoxic nitrosamine impurities levels have been a mandatory quality and safety characteristic for various drugs. The main issue of nitrosamine determination in drugs is a low sensitivity of the existing methods and a continuously extending list of controlled c...

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Detalles Bibliográficos
Autores principales:	Khorolskiy, Mikhail, Ramenskaya, Galina, Vlasov, Alexander, Perederyaev, Oleg, Maslennikova, Nataliya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653666/ https://www.ncbi.nlm.nih.gov/pubmed/34904007 http://dx.doi.org/10.22037/ijpr.2021.115102.15195

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