Cargando…

Development and Validation of four Nitrosamine Impurities Determination Method in Medicines of Valsartan, Losartan, and Irbesartan with HPLC-MS/MS (APCI)

Since 2018, regulation and control of genotoxic nitrosamine impurities levels have been a mandatory quality and safety characteristic for various drugs. The main issue of nitrosamine determination in drugs is a low sensitivity of the existing methods and a continuously extending list of controlled c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khorolskiy, Mikhail, Ramenskaya, Galina, Vlasov, Alexander, Perederyaev, Oleg, Maslennikova, Nataliya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653666/ https://www.ncbi.nlm.nih.gov/pubmed/34904007 http://dx.doi.org/10.22037/ijpr.2021.115102.15195

Ejemplares similares

Valsartan, Losartan and Irbesartan use in the USA, UK, Canada and Denmark after the nitrosamine recalls: a descriptive cohort study
por: Eworuke, Efe, et al.
Publicado: (2023)

Comparison of EI-GC-MS/MS, APCI-LC-MS/MS, and ESI-LC-MS/MS for the Simultaneous Analysis of Nine Nitrosamines Eluted from Synthetic Resins into Artificial Saliva and Health Risk Assessment
por: Kim, Hyungsoo, et al.
Publicado: (2021)

Cost-effective, green HPLC determination of losartan, valsartan and their nitrosodiethylamine impurity: application to pharmaceutical dosage forms
por: Abd El-Hay, Soad S., et al.
Publicado: (2022)

Simultaneous Determination of 15 Sulfonate Ester Impurities in Phentolamine Mesylate, Amlodipine Besylate, and Tosufloxacin Tosylate by LC-APCI-MS/MS
por: Jin, Bo, et al.
Publicado: (2019)

Quali-Quantitative Profile of Native Carotenoids in Kumquat from Brazil by HPLC-DAD-APCI/MS
por: Pinheiro-Sant’Ana, Helena Maria, et al.
Publicado: (2019)

Comparative Study for the Determination of Fat-Soluble Vitamins in Rice Cereal Baby Foods Using HPLC-DAD and UHPLC-APCI-MS/MS
por: Katsa, Maria, et al.
Publicado: (2021)

Risk of myocardial infarction, heart failure, and cerebrovascular disease with the use of valsartan, losartan, irbesartan, and telmisartan in patients
por: Yoo, Yung-Geun, et al.
Publicado: (2023)

Development and validation of an APCI-MS/GC–MS approach for the classification and prediction of Cheddar cheese maturity
por: Gan, Heng Hui, et al.
Publicado: (2016)

Comparison of ESI– and APCI–LC–MS/MS methods: A case study of levonorgestrel in human plasma()
por: Wang, Rulin, et al.
Publicado: (2016)

HPLC-UV/Vis-APCI-MS/MS Determination of Major Carotenoids and Their Bioaccessibility from “Delica” (Cucurbita maxima) and “Violina” (Cucurbita moschata) Pumpkins as Food Traceability Markers
por: Bergantin, Caterina, et al.
Publicado: (2018)

Unravelling the Distribution of Secondary Metabolites in Olea europaea L.: Exhaustive Characterization of Eight Olive-Tree Derived Matrices by Complementary Platforms (LC-ESI/APCI-MS and GC-APCI-MS)
por: Olmo-García, Lucía, et al.
Publicado: (2018)

Presence of Nitrosamine Impurities in Medicinal Products
por: Sedlo, Ilijana, et al.
Publicado: (2021)

Systematic Approach for Trace Level Quantification of 2-N-butyl-4-spirocyclopentane-2-imidazole-5-one Genotoxic Impurity in Irbesartan Using LC-MS/MS
por: Reddy, A. Vijaya Bhaskar, et al.
Publicado: (2013)

Identification of Absorbed Constituents in the Rabbit Plasma and Cerebrospinal Fluid after Intranasal Administration of Asari Radix et Rhizoma by HS-SPME-GC-MS and HPLC-APCI-IT-TOF-MS(n)
por: Li, Chen, et al.
Publicado: (2014)

Structural Characterization of Unusual Fatty Acid Methyl Esters with Double and Triple Bonds Using HPLC/APCI-MS(2) with Acetonitrile In-Source Derivatization
por: Horká, Petra, et al.
Publicado: (2021)

Rapid Determination of Six Low Molecular Carbonyl Compounds in Tobacco Smoke by the APCI-MS/MS Coupled to Data Mining
por: Zhao, Wuduo, et al.
Publicado: (2017)

Stability profiling of anti-malarial drug piperaquine phosphate and impurities by HPLC-UV, TOF-MS, ESI-MS and NMR
por: Yan, Fang, et al.
Publicado: (2014)

LC-APCI-MS method for detection and analysis of tryptanthrin, indigo, and indirubin in Daqingye and Banlangen
por: Liau, Bing-Chung, et al.
Publicado: (2007)

The EU Response to the Presence of Nitrosamine Impurities in Medicines
por: Ruepp, Robin, et al.
Publicado: (2021)

A multi-analyte LC-MS/MS method for screening and quantification of nitrosamines in sartans
por: Chang, Shu-Han, et al.
Publicado: (2020)

Effects of Xuesaitong on the Pharmacokinetics of Losartan: An In Vivo UPLC-MS/MS Study
por: Ma, Weina, et al.
Publicado: (2019)

A Case of Sprue-like Enteropathy Associated With Valsartan and Irbesartan
por: Yoo, Seo Yeon, et al.
Publicado: (2022)

Chromatographic behavior of co-eluted plasma compounds and effect on screening of drugs by APCI-LC–MS(/MS): Applications to selected cardiovascular drugs
por: Tahboub, Yahya R.
Publicado: (2014)

Simultaneous Quantitation of S(+)- and R(−)-Baclofen and Its Metabolite in Human Plasma and Cerebrospinal Fluid using LC–APCI–MS/MS: An Application for Clinical Studies
por: He, Qingfeng, et al.
Publicado: (2020)

A Flexible Tool to Correct Superimposed Mass Isotopologue Distributions in GC-APCI-MS Flux Experiments
por: Langenhan, Jennifer, et al.
Publicado: (2022)

Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine
por: Verbeken, Mathieu, et al.
Publicado: (2011)

Identification of impurities in nafamostat mesylate using HPLC-IT-TOF/MS: A series of double-charged ions
por: Zhang, Yuxin, et al.
Publicado: (2020)

Simultaneous determination of losartan, losartan acid and amlodipine in human plasma by LC-MS/MS and its application to a human pharmacokinetic study
por: Karra, Vijaya Kumari, et al.
Publicado: (2012)

Development and Validation of 2-Azaspiro [4,5] Decan-3-One (Impurity A) in Gabapentin Determination Method Using qNMR Spectroscopy
por: Kuz’mina, Nataliya E., et al.
Publicado: (2021)

Effect of Position 1 Substituent and Configuration on APCI–MS Fragmentation of Norditerpenoid Alkaloids Including 1-epi-Condelphine
por: Qasem, Ashraf M. A., et al.
Publicado: (2022)

Identification of Unknown Impurity of Azelaic Acid in Liposomal Formulation Assessed by HPLC-ELSD, GC-FID, and GC-MS
por: Han, Stanisław, et al.
Publicado: (2013)

Determination of Oseltamivir in Human Plasma by HPLC-MS/MS
por: Lakeev, A. P., et al.
Publicado: (2023)

Phase II Metabolism of Asarone Isomers In Vitro and in Humans Using HPLC-MS/MS and HPLC-qToF/MS
por: Hermes, Lena, et al.
Publicado: (2021)

Novel Conjugates of 1,3-Diacylglycerol and Lipoic Acid: Synthesis, DPPH Assay, and RP-LC-MS-APCI Analysis
por: Madawala, Samanthi R. P., et al.
Publicado: (2011)

UHPLC-MS/MS method for the simultaneous determination of nicotine and tobacco-specific nitrosamines NNN and NNK for use in preclinical studies
por: Meikopoulos, Thomas, et al.
Publicado: (2022)

LC–MS/MS analysis of carcinogenic tobacco-specific nitrosamines in Spodoptera litura using the QuEChERS method
por: Battu, Jabez Raju, et al.
Publicado: (2023)

Production of the Quinone-Methide Triterpene Maytenin by In Vitro Adventitious Roots of Peritassa campestris (Cambess.) A.C.Sm. (Celastraceae) and Rapid Detection and Identification by APCI-IT-MS/MS
por: Paz, Tiago Antunes, et al.
Publicado: (2013)

Development of HPLC-CAD method for simultaneous quantification of nine related substances in ursodeoxycholic acid and identification of two unknown impurities by HPLC-Q-TOF-MS
por: Huang, Yiwen, et al.
Publicado: (2023)

Synthesis, isolation, identification and characterization of new process-related impurity in isoproterenol hydrochloride by HPLC, LC/ESI-MS and NMR
por: Kumar, Neeraj, et al.
Publicado: (2017)

Development and Validation of Ecofriendly HPLC-MS Method for Quantitative Assay of Amoxicillin, Dicloxacillin, and Their Official Impurity in Pure and Dosage Forms
por: Almalki, Atiah H., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ggtofl9g2s5pmvtu5sv5fkmqab