SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage

Mounting evidence has suggested that modulating microglia polarization from pro-inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic approach in the treatment of subarachnoid hemorrhage (SAH) injury. Our previous study has indicated that sirtuin 1 (SIRT1) could am...

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Detalles Bibliográficos
Autores principales: Xia, Da-Yong, Yuan, Jin-Long, Jiang, Xiao-Chun, Qi, Min, Lai, Nian-Sheng, Wu, Ling-Yun, Zhang, Xiang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653696/
https://www.ncbi.nlm.nih.gov/pubmed/34899720
http://dx.doi.org/10.3389/fimmu.2021.770744

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