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A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease

INTRODUCTION: Leprosy is a chronic disease caused by mycobacterium leprae. Chronicity of the disease leads to various psychiatric co-morbidities, which are often undiagnosed and untreated. The main objectives of this study were to evaluate the frequency and nature of psychiatric co-morbidity in pati...

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Autores principales: Rani, Ritu, Tegta, Gita R., Verma, Ghanshyam K., Sharma, Dinesh D., Gupta, Mudita, Negi, Ajeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653717/
https://www.ncbi.nlm.nih.gov/pubmed/34934720
http://dx.doi.org/10.4103/idoj.IDOJ_141_21
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author Rani, Ritu
Tegta, Gita R.
Verma, Ghanshyam K.
Sharma, Dinesh D.
Gupta, Mudita
Negi, Ajeet
author_facet Rani, Ritu
Tegta, Gita R.
Verma, Ghanshyam K.
Sharma, Dinesh D.
Gupta, Mudita
Negi, Ajeet
author_sort Rani, Ritu
collection PubMed
description INTRODUCTION: Leprosy is a chronic disease caused by mycobacterium leprae. Chronicity of the disease leads to various psychiatric co-morbidities, which are often undiagnosed and untreated. The main objectives of this study were to evaluate the frequency and nature of psychiatric co-morbidity in patients of Hansen's disease. MATERIALS AND METHODS: Seventy confirmed cases of Hansen's disease between the ages of 18 and 60 years attending the department of dermatology of Indira Gandhi Medical College and Hospital, Shimla were evaluated for various manifestations of Hansen's disease and screened for psychiatric co-morbidity using GHQ-12 and diagnosed using ICD-10 checklist. Severity of depression and anxiety was assessed with HAM-D and HAM-A scales, respectively. RESULTS: The prevalence of psychiatric co-morbidity was found in 27.14% of enrolled patients. Depression was most prevalent in (20%) mental disorder; followed by anxiety disorder (7.14%). Moderate depressive episode was the commonest seen in 11.42% patients whereas 5.71% patients had mild depression. Generalized anxiety disorder was seen in 1.42% whereas 5.71% patients had mixed anxiety disorder. Patients with higher education status, positive family history of leprosy, lepromatous leprosy, and hand deformities were significantly associated with higher psychiatric co-morbidity. CONCLUSION: Patients suffering from Hansen's disease have significantly high prevalence of psychiatric co-morbidity complicating the Hansen's disease. High index of suspicion is required to diagnose and treat it.
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spelling pubmed-86537172021-12-20 A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease Rani, Ritu Tegta, Gita R. Verma, Ghanshyam K. Sharma, Dinesh D. Gupta, Mudita Negi, Ajeet Indian Dermatol Online J Original Article INTRODUCTION: Leprosy is a chronic disease caused by mycobacterium leprae. Chronicity of the disease leads to various psychiatric co-morbidities, which are often undiagnosed and untreated. The main objectives of this study were to evaluate the frequency and nature of psychiatric co-morbidity in patients of Hansen's disease. MATERIALS AND METHODS: Seventy confirmed cases of Hansen's disease between the ages of 18 and 60 years attending the department of dermatology of Indira Gandhi Medical College and Hospital, Shimla were evaluated for various manifestations of Hansen's disease and screened for psychiatric co-morbidity using GHQ-12 and diagnosed using ICD-10 checklist. Severity of depression and anxiety was assessed with HAM-D and HAM-A scales, respectively. RESULTS: The prevalence of psychiatric co-morbidity was found in 27.14% of enrolled patients. Depression was most prevalent in (20%) mental disorder; followed by anxiety disorder (7.14%). Moderate depressive episode was the commonest seen in 11.42% patients whereas 5.71% patients had mild depression. Generalized anxiety disorder was seen in 1.42% whereas 5.71% patients had mixed anxiety disorder. Patients with higher education status, positive family history of leprosy, lepromatous leprosy, and hand deformities were significantly associated with higher psychiatric co-morbidity. CONCLUSION: Patients suffering from Hansen's disease have significantly high prevalence of psychiatric co-morbidity complicating the Hansen's disease. High index of suspicion is required to diagnose and treat it. Wolters Kluwer - Medknow 2021-11-22 /pmc/articles/PMC8653717/ /pubmed/34934720 http://dx.doi.org/10.4103/idoj.IDOJ_141_21 Text en Copyright: © 2021 Indian Dermatology Online Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Rani, Ritu
Tegta, Gita R.
Verma, Ghanshyam K.
Sharma, Dinesh D.
Gupta, Mudita
Negi, Ajeet
A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease
title A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease
title_full A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease
title_fullStr A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease
title_full_unstemmed A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease
title_short A Clinicoepidemiological Study of Psychiatric Co-Morbidity in Hansen's Disease
title_sort clinicoepidemiological study of psychiatric co-morbidity in hansen's disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653717/
https://www.ncbi.nlm.nih.gov/pubmed/34934720
http://dx.doi.org/10.4103/idoj.IDOJ_141_21
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