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Time is of the essence: the molecular mechanisms of primary microcephaly

Primary microcephaly is a brain growth disorder characterized by a severe reduction of brain size and thinning of the cerebral cortex. Many primary microcephaly mutations occur in genes that encode centrosome proteins, highlighting an important role for centrosomes in cortical development. Centrosom...

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Detalles Bibliográficos
Autores principales: Phan, Thao P., Holland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653793/
https://www.ncbi.nlm.nih.gov/pubmed/34862179
http://dx.doi.org/10.1101/gad.348866.121

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