SAP domain forms a flexible part of DNA aperture in Ku70/80

Nonhomologous end joining (NHEJ) is a DNA repair mechanism that religates double‐strand DNA breaks to maintain genomic integrity during the entire cell cycle. The Ku70/80 complex recognizes DNA breaks and serves as an essential hub for recruitment of NHEJ components. Here, we describe intramolecular...

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Detalles Bibliográficos
Autores principales: Hnízda, Aleš, Tesina, Petr, Nguyen, Thanh‐Binh, Kukačka, Zdeněk, Kater, Lukas, Chaplin, Amanda K., Beckmann, Roland, Ascher, David B., Novák, Petr, Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653891/
https://www.ncbi.nlm.nih.gov/pubmed/33511782
http://dx.doi.org/10.1111/febs.15732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653891/
https://www.ncbi.nlm.nih.gov/pubmed/33511782
http://dx.doi.org/10.1111/febs.15732

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