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SAP domain forms a flexible part of DNA aperture in Ku70/80

Nonhomologous end joining (NHEJ) is a DNA repair mechanism that religates double‐strand DNA breaks to maintain genomic integrity during the entire cell cycle. The Ku70/80 complex recognizes DNA breaks and serves as an essential hub for recruitment of NHEJ components. Here, we describe intramolecular...

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Detalles Bibliográficos
Autores principales:	Hnízda, Aleš, Tesina, Petr, Nguyen, Thanh‐Binh, Kukačka, Zdeněk, Kater, Lukas, Chaplin, Amanda K., Beckmann, Roland, Ascher, David B., Novák, Petr, Blundell, Tom L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653891/ https://www.ncbi.nlm.nih.gov/pubmed/33511782 http://dx.doi.org/10.1111/febs.15732

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