Cargando…

Dibenzocycloheptanones construction through a removable P-centered radical: synthesis of allocolchicine analogues

Dibenzocycloheptanones containing a tricyclic 6–7–6-system are present in numerous biologically active natural molecules. However, the simple and efficient preparation of derivatives containing a dibenzocycloheptanone scaffold remains difficult to date. Herein, we report a versatile strategy for the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yan, Cai, Zhenzhi, Struwe, Julia, Ma, Chanchan, Zeng, Wangyu, Liao, Xinyi, Xu, Min, Ackermann, Lutz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654019/ https://www.ncbi.nlm.nih.gov/pubmed/35003604 http://dx.doi.org/10.1039/d1sc05404j

Ejemplares similares

Electrooxidative tricyclic 6–7–6 fused-system domino assembly to allocolchicines by a removable radical strategy
por: Zhang, Yan, et al.
Publicado: (2022)

Total Synthesis of (±)-Allocolchicine and Its Analogues Using Co-Catalyzed Alkyne [2 + 2 + 2]-Cyclotrimerization
por: Paymode, Dinesh J., et al.
Publicado: (2017)

Electrooxidative dearomatization of biaryls: synthesis of tri- and difluoromethylated spiro[5.5]trienones
por: Zhang, Yan, et al.
Publicado: (2021)

Electrosynthesis of bridged or fused sulfonamides through complex radical cascade reactions: divergence in medium-sized ring formation
por: Zhang, Yan, et al.
Publicado: (2023)

Formal Synthesis of (±)-Allocolchicine Via Gold-Catalysed Direct Arylation: Implication of Aryl Iodine(III) Oxidant in Catalyst Deactivation Pathways
por: Corrie, Tom J. A., et al.
Publicado: (2017)

Rhodium‐Catalyzed Electrooxidative C−H Olefination of Benzamides
por: Zhang, Yan, et al.
Publicado: (2020)

Nickela‐electrocatalyzed Mild C−H Alkylations at Room Temperature
por: Samanta, Ramesh C., et al.
Publicado: (2020)

Photo‐Induced Ruthenium‐Catalyzed C−H Benzylations and Allylations at Room Temperature
por: Struwe, Julia, et al.
Publicado: (2021)

Nickela‐electrocatalyzed C−H Alkoxylation with Secondary Alcohols: Oxidation‐Induced Reductive Elimination at Nickel(III)
por: Zhang, Shou‐Kun, et al.
Publicado: (2020)

Removing the no-analogue bias in modern accelerated tree growth leads to stronger medieval drought
por: Scharnweber, Tobias, et al.
Publicado: (2019)

Regiodivergent C−H and Decarboxylative C−C Alkylation by Ruthenium Catalysis: ortho versus meta Position‐Selectivity
por: Korvorapun, Korkit, et al.
Publicado: (2020)

Photo‐Induced Ruthenium‐Catalyzed C−H Arylations at Ambient Temperature
por: Korvorapun, Korkit, et al.
Publicado: (2020)

Cobalt-catalyzed radical-mediated carbon–carbon scission via a radical-type migratory insertion
por: Liu, Jian-Biao, et al.
Publicado: (2023)

Radical‐free hyperpolarized MRI using endogenously occurring pyruvate analogues and UV‐induced nonpersistent radicals
por: Zanella, Claudia C., et al.
Publicado: (2021)

Substituted Benzimidazole Analogues as Potential α-Amylase Inhibitors and Radical Scavengers
por: Akande, Akinsola Adegboye, et al.
Publicado: (2021)

Postoperative stellate ganglion block to reduce myocardial injury after laparoscopic radical resection for colorectal cancer: protocol for a randomised trial
por: Hu, Zhouting, et al.
Publicado: (2023)

Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors
por: Islam, Mohammad Shahidul, et al.
Publicado: (2021)

Iminyl radical-triggered relay annulation for the construction of bridged aza-tetracycles bearing four contiguous stereogenic centers
por: Jiang, Kun, et al.
Publicado: (2022)

Evolutionary Games of Low-Carbon Behaviors of Construction Stakeholders under Carbon Taxes
por: Du, Qiang, et al.
Publicado: (2021)

Photo‐Induced Ruthenium‐Catalyzed Double Remote C(sp(2))−H / C(sp(3))−H Functionalizations by Radical Relay
por: Wang, Yulei, et al.
Publicado: (2022)

Migratory functionalization of unactivated alkyl bromides for construction of all-carbon quaternary centers via transposed tert-C-radicals
por: Zhu, Chuan, et al.
Publicado: (2020)

Effects of sphingosine and sphingosine analogues on the free radical production by stimulated neutrophils: ESR and chemiluminescence studies
por: Mouithys-Mickalad, A., et al.
Publicado: (1997)

Removal of Pharmaceutical Products in a Constructed Wetland
por: Özengin, Nihan, et al.
Publicado: (2016)

Carbon-Centered Radicals in Protein Manipulation
por: Chen, Xuanxiao, et al.
Publicado: (2023)

Copper-mediated oxidative C−H/N−H activations with alkynes by removable hydrazides
por: Xiong, Feng, et al.
Publicado: (2021)

Design, synthesis and biological evaluation of chalcone analogues with novel dual antioxidant mechanisms as potential anti-ischemic stroke agents
por: Wang, Jiabing, et al.
Publicado: (2019)

Phenylpropanoid Glycoside Analogues: Enzymatic Synthesis, Antioxidant Activity and Theoretical Study of Their Free Radical Scavenger Mechanism
por: López-Munguía, Agustín, et al.
Publicado: (2011)

A Computational Study of Structure and Reactivity of N-Substitued-4-Piperidones Curcumin Analogues and Their Radical Anions
por: Martínez-Cifuentes, Maximiliano, et al.
Publicado: (2016)

Enhancing the sensitization of neuroblastoma to radiotherapy by the construction of a dual-channel parallel free radicals nanoamplifier
por: Zhang, Wenxin, et al.
Publicado: (2023)

Design, Operation and Optimization of Constructed Wetland for Removal of Pollutant
por: Rahman, Md Ekhlasur, et al.
Publicado: (2020)

The role of nitric oxide radicals in removal of hyper-radiosensitivity by priming irradiation
por: Edin, Nina Jeppesen, et al.
Publicado: (2013)

Large and giant skull base meningiomas: The role of radical surgical removal
por: da Silva, Carlos Eduardo, et al.
Publicado: (2015)

Operation for Strangulated Hernia; Removal of Hernial Sac, Followed by Radical Cure
por: Miner, J. F.
Publicado: (1863)

Magnetic Nanocomposites for the Remote Activation of Sulfate Radicals for the Removal of Rhodamine B
por: Paul, Pranto, et al.
Publicado: (2023)

Efficacy of insulin analogues in diabetic patients attending primary care centers
por: Bardisi, Wedad M., et al.
Publicado: (2015)

Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China
por: Wang, Shucai, et al.
Publicado: (2021)

Synthesis of a Complex Brasilicardin Analogue Utilizing a Cobalt-Catalyzed MHAT-Induced Radical Bicyclization Reaction
por: Niman, Scott W., et al.
Publicado: (2023)

Stable construction of the sternum after broad radical resection of malignant tumours
por: Tulner, Sven A.F., et al.
Publicado: (2013)

Comparative Study on the Efficiency of Mercury Removal From Wastewater Using Bacterial Cellulose Membranes and Their Oxidized Analogue
por: Suárez-Avendaño, D., et al.
Publicado: (2022)

Safe Removal of the Urethral Catheter 2 Days Following Laparoscopic Radical Prostatectomy
por: James, Philip, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_thc8j5adop3g1p8h2m2po9h33g