T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam

T-cell large granular lymphocytic leukemia (T-LGL leukemia) is a rare, chronic lymphoproliferative disorder in the peripheral blood. This is characterized by peripheral blood and bone marrow (BM) lymphocytic infiltration with clonal large granular lymphocytes (LGLs). The neoplastic cells of this dis...

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Detalles Bibliográficos
Autores principales: Vinh An, Do T, Lan Anh, Le, Tuan Tung, Nguyen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654106/
https://www.ncbi.nlm.nih.gov/pubmed/34926089
http://dx.doi.org/10.7759/cureus.20249
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author Vinh An, Do T
Lan Anh, Le
Tuan Tung, Nguyen
author_facet Vinh An, Do T
Lan Anh, Le
Tuan Tung, Nguyen
author_sort Vinh An, Do T
collection PubMed
description T-cell large granular lymphocytic leukemia (T-LGL leukemia) is a rare, chronic lymphoproliferative disorder in the peripheral blood. This is characterized by peripheral blood and bone marrow (BM) lymphocytic infiltration with clonal large granular lymphocytes (LGLs). The neoplastic cells of this disease display a mature T-cell immunophenotype, with the majority of cases showing a CD4-/CD8+ T-cell, T-cell receptor (TCR) subset immunophenotype versus other permutations of those markers.
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spelling pubmed-86541062021-12-17 T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam Vinh An, Do T Lan Anh, Le Tuan Tung, Nguyen Cureus Pathology T-cell large granular lymphocytic leukemia (T-LGL leukemia) is a rare, chronic lymphoproliferative disorder in the peripheral blood. This is characterized by peripheral blood and bone marrow (BM) lymphocytic infiltration with clonal large granular lymphocytes (LGLs). The neoplastic cells of this disease display a mature T-cell immunophenotype, with the majority of cases showing a CD4-/CD8+ T-cell, T-cell receptor (TCR) subset immunophenotype versus other permutations of those markers. Cureus 2021-12-07 /pmc/articles/PMC8654106/ /pubmed/34926089 http://dx.doi.org/10.7759/cureus.20249 Text en Copyright © 2021, Vinh An et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Vinh An, Do T
Lan Anh, Le
Tuan Tung, Nguyen
T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam
title T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam
title_full T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam
title_fullStr T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam
title_full_unstemmed T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam
title_short T-Cell Large Granular Lymphocytic Leukemia: A First Case Report Diagnosed by Flow Cytometry in Vietnam
title_sort t-cell large granular lymphocytic leukemia: a first case report diagnosed by flow cytometry in vietnam
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654106/
https://www.ncbi.nlm.nih.gov/pubmed/34926089
http://dx.doi.org/10.7759/cureus.20249
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AT lananhle tcelllargegranularlymphocyticleukemiaafirstcasereportdiagnosedbyflowcytometryinvietnam
AT tuantungnguyen tcelllargegranularlymphocyticleukemiaafirstcasereportdiagnosedbyflowcytometryinvietnam

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