A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience

Fanconi anemia (FA) is a disease that could be accompanied by multiple abnormalities, such as growth retardation, bone marrow abnormalities, and cancer susceptibility. Among the FA patients, head and neck squamous cell cancer (HNSCC) is the most observed solid cancer. The life expectancy of patients...

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Autores principales: Kavak, Gizem, Basci, Semih, Türker Kekilli, Esra, Dal, Mehmet S, Karakaya, Ebru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654145/
https://www.ncbi.nlm.nih.gov/pubmed/34925988
http://dx.doi.org/10.7759/cureus.19386
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author Kavak, Gizem
Basci, Semih
Türker Kekilli, Esra
Dal, Mehmet S
Karakaya, Ebru
author_facet Kavak, Gizem
Basci, Semih
Türker Kekilli, Esra
Dal, Mehmet S
Karakaya, Ebru
author_sort Kavak, Gizem
collection PubMed
description Fanconi anemia (FA) is a disease that could be accompanied by multiple abnormalities, such as growth retardation, bone marrow abnormalities, and cancer susceptibility. Among the FA patients, head and neck squamous cell cancer (HNSCC) is the most observed solid cancer. The life expectancy of patients with FA has increased with recent medical advances. Furthermore, HNSCC is diagnosed in 3% of FA patients, and half of these patients die because of their HNSCC. The median age of HNSCC patients with FA is 31, and according to the literature HNSCC incidence of FA, patients is more than 700-fold of the normal population. Here, we reported the treatment details and challenges we faced during hypopharyngeal cancer treatment in a FA patient.
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spelling pubmed-86541452021-12-17 A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience Kavak, Gizem Basci, Semih Türker Kekilli, Esra Dal, Mehmet S Karakaya, Ebru Cureus Radiation Oncology Fanconi anemia (FA) is a disease that could be accompanied by multiple abnormalities, such as growth retardation, bone marrow abnormalities, and cancer susceptibility. Among the FA patients, head and neck squamous cell cancer (HNSCC) is the most observed solid cancer. The life expectancy of patients with FA has increased with recent medical advances. Furthermore, HNSCC is diagnosed in 3% of FA patients, and half of these patients die because of their HNSCC. The median age of HNSCC patients with FA is 31, and according to the literature HNSCC incidence of FA, patients is more than 700-fold of the normal population. Here, we reported the treatment details and challenges we faced during hypopharyngeal cancer treatment in a FA patient. Cureus 2021-11-09 /pmc/articles/PMC8654145/ /pubmed/34925988 http://dx.doi.org/10.7759/cureus.19386 Text en Copyright © 2021, Kavak et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Kavak, Gizem
Basci, Semih
Türker Kekilli, Esra
Dal, Mehmet S
Karakaya, Ebru
A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience
title A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience
title_full A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience
title_fullStr A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience
title_full_unstemmed A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience
title_short A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience
title_sort case of hypopharyngeal cancer associated with fanconi anemia: a helical tomotherapy experience
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654145/
https://www.ncbi.nlm.nih.gov/pubmed/34925988
http://dx.doi.org/10.7759/cureus.19386
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