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The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology

The cancer-associated fibroblast (CAF) marker podoplanin (PDPN) is generally correlated with poor clinical outcomes in cancer patients and thus represents a promising therapeutic target. Despite its biomedical relevance, basic aspects of PDPN biology such as its cellular functions and cell surface l...

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Detalles Bibliográficos
Autores principales: Astarita, Jillian L., Keerthivasan, Shilpa, Husain, Bushra, Şenbabaoğlu, Yasin, Verschueren, Erik, Gierke, Sarah, Pham, Victoria C., Peterson, Sean M., Chalouni, Cecile, Pierce, Andrew A., Lill, Jennie R., Gonzalez, Lino C., Martinez-Martin, Nadia, Turley, Shannon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654239/
https://www.ncbi.nlm.nih.gov/pubmed/34879110
http://dx.doi.org/10.1371/journal.pone.0260800

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