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The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology
The cancer-associated fibroblast (CAF) marker podoplanin (PDPN) is generally correlated with poor clinical outcomes in cancer patients and thus represents a promising therapeutic target. Despite its biomedical relevance, basic aspects of PDPN biology such as its cellular functions and cell surface l...
Autores principales: | Astarita, Jillian L., Keerthivasan, Shilpa, Husain, Bushra, Şenbabaoğlu, Yasin, Verschueren, Erik, Gierke, Sarah, Pham, Victoria C., Peterson, Sean M., Chalouni, Cecile, Pierce, Andrew A., Lill, Jennie R., Gonzalez, Lino C., Martinez-Martin, Nadia, Turley, Shannon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654239/ https://www.ncbi.nlm.nih.gov/pubmed/34879110 http://dx.doi.org/10.1371/journal.pone.0260800 |
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