Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48

Dysregulated mitochondrial function is a hallmark of immune-mediated inflammatory diseases. Cytochrome c oxidase (CcO), which mediates the rate-limiting step in mitochondrial respiration, is remodeled during development and in response to changes of oxygen availability, but there has been little stu...

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Detalles Bibliográficos
Autores principales: Clayton, Sally A., Daley, Kalbinder K., MacDonald, Lucy, Fernandez-Vizarra, Erika, Bottegoni, Giovanni, O’Neil, John D., Major, Triin, Griffin, Daniel, Zhuang, Qinqin, Adewoye, Adeolu B., Woolcock, Kieran, Jones, Simon W., Goodyear, Carl, Elmesmari, Aziza, Filer, Andrew, Tennant, Daniel A., Alivernini, Stefano, Buckley, Christopher D., Pitceathly, Robert D. S., Kurowska-Stolarska, Mariola, Clark, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654286/
https://www.ncbi.nlm.nih.gov/pubmed/34878835
http://dx.doi.org/10.1126/sciadv.abl5182

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