Cargando…

Injury-induced ASCL1 expression orchestrates a transitory cell state required for repair of the neonatal cerebellum

To understand repair processes, it is critical to identify the molecular foundations underlying progenitor diversity and plasticity. Upon injury to the neonatal cerebellum, a normally gliogenic nestin-expressing progenitor (NEP) in the Bergmann glia layer (BgL) undergoes adaptive reprograming to res...

Descripción completa

Detalles Bibliográficos
Autores principales: Bayin, N. Sumru, Mizrak, Dogukan, Stephen, Daniel N., Lao, Zhimin, Sims, Peter A., Joyner, Alexandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654303/
https://www.ncbi.nlm.nih.gov/pubmed/34878841
http://dx.doi.org/10.1126/sciadv.abj1598