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Injury-induced ASCL1 expression orchestrates a transitory cell state required for repair of the neonatal cerebellum
To understand repair processes, it is critical to identify the molecular foundations underlying progenitor diversity and plasticity. Upon injury to the neonatal cerebellum, a normally gliogenic nestin-expressing progenitor (NEP) in the Bergmann glia layer (BgL) undergoes adaptive reprograming to res...
Autores principales: | Bayin, N. Sumru, Mizrak, Dogukan, Stephen, Daniel N., Lao, Zhimin, Sims, Peter A., Joyner, Alexandra L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654303/ https://www.ncbi.nlm.nih.gov/pubmed/34878841 http://dx.doi.org/10.1126/sciadv.abj1598 |
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