Cargando…

Characterization of a Novel Model of Lumbar Ligamentum Flavum Hypertrophy in Bipedal Standing Mice

OBJECTIVE: To explore the main causes of hypertrophied ligamentum flavum (HLF) and the possibility of using bipedal standing mouse model to simulate the pathological changes in human HLF. METHODS: Thirty‐two 8‐week‐old C57BL/6 male mice were randomly assigned to the experimental group (n = 16) and c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Zhen‐yu, Li, Peng, Ao, Xiang, Qian, Lei, Peng, Yong‐xing, Chu, Jun, Jiang, Tao, Lian, Zheng‐nan, Zhang, Zhong‐min, Wang, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654658/ https://www.ncbi.nlm.nih.gov/pubmed/34651434 http://dx.doi.org/10.1111/os.13156

Ejemplares similares

CRLF1 Is a Key Regulator in the Ligamentum Flavum Hypertrophy
por: Zheng, Zhenyu, et al.
Publicado: (2020)

Experimental Mouse Model of Lumbar Ligamentum Flavum Hypertrophy
por: Saito, Takeyuki, et al.
Publicado: (2017)

Macrophage migration inhibitory factor takes part in the lumbar ligamentum flavum hypertrophy
por: Lu, Qi-Lin, et al.
Publicado: (2022)

Relationship between the location of ligamentum flavum hypertrophy and its stress in finite element analysis
por: Peng, Yong‐xing, et al.
Publicado: (2020)

Revealing the novel autophagy-related genes for ligamentum flavum hypertrophy in patients and mice model
por: Li, Peng, et al.
Publicado: (2022)

Hypertrophy of Ligamentum Flavum in Lumbar Spine Stenosis Is Associated with Increased miR-155 Level
por: Chen, Jianwei, et al.
Publicado: (2014)

The paradoxical relationship between ligamentum flavum hypertrophy and developmental lumbar spinal stenosis
por: Cheung, Prudence Wing Hang, et al.
Publicado: (2016)

The increased motion of lumbar induces ligamentum flavum hypertrophy in a rat model
por: Wang, Baojian, et al.
Publicado: (2021)

Ossification of the Ligamentum Flavum of the Lumbar Spine
por: Sidronio, Talles, et al.
Publicado: (2021)

Analysis of the Relationship between Hypertrophy of the Ligamentum Flavum and Lumbar Segmental Motion with Aging Process
por: Yoshiiwa, Toyomi, et al.
Publicado: (2016)

MicroRNA transcriptome analysis on hypertrophy of ligamentum flavum in patients with lumbar spinal stenosis
por: Mori, Taiki, et al.
Publicado: (2017)

The Difference in Gender Affects the Pathogenesis of Ligamentum Flavum Hypertrophy
por: Takashima, Hiroyuki, et al.
Publicado: (2018)

Potential Involvement of Oxidative Stress in Ligamentum Flavum Hypertrophy
por: Ito, Kei, et al.
Publicado: (2023)

Clusterin negatively modulates mechanical stress-mediated ligamentum flavum hypertrophy through TGF-β1 signaling
por: Liu, Chunlei, et al.
Publicado: (2022)

Phenotypic Characterization of Ligamentum Flavum Cells from Patients with Ossification of Ligamentum Flavum
por: Zhong, Zhao-Ming, et al.
Publicado: (2009)

Decreased catalase expression is associated with ligamentum flavum hypertrophy due to lumbar spinal canal stenosis
por: Yücetaş, Şeyho Cem, et al.
Publicado: (2019)

Hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis is associated with abnormal accumulation of specific lipids
por: Yamada, Tomohiro, et al.
Publicado: (2021)

Relationship between Severity of Lumbar Spinal Stenosis and Ligamentum Flavum Hypertrophy and Serum Inflammatory Factors
por: He, Nina, et al.
Publicado: (2022)

Percutaneous Lumbar Decompression With SpineJet Hydrosurgery in the Treatment of Lumbar Spinal Stenosis Secondary to Ligamentum Flavum Hypertrophy
por: Vaisman, Julien, et al.
Publicado: (2016)

Hypertrophy of the ligamentum flavum and expression of transforming growth factor beta
por: Amudong, Aierken, et al.
Publicado: (2017)

Haemorrhagic Lumbar Juxtafacet Cyst with Ligamentum Flavum Involvement
por: Ghent, Finn, et al.
Publicado: (2014)

Macrophage migration inhibitory factor may contribute to hypertrophy of lumbar ligamentum flavum in type 2 diabetes mellitus
por: Lu, Qi-Lin, et al.
Publicado: (2020)

Radiological Significance of Ligamentum Flavum Hypertrophy in the Occurrence of Redundant Nerve Roots of Central Lumbar Spinal Stenosis
por: Hur, Junseok W, et al.
Publicado: (2012)

Ossification of the Ligamentum Flavum
por: Ahn, Dong Ki, et al.
Publicado: (2014)

Ossification of the ligamentum flavum
por: Hirabayashi, Shigeru
Publicado: (2017)

Immune cell infiltration and the genes associated with ligamentum flavum hypertrophy: Identification and validation
por: Duan, Yang, et al.
Publicado: (2022)

Ligamentum Flavum Hypertrophy in Asymptomatic and Chronic Low Back Pain Subjects
por: Munns, Justin J., et al.
Publicado: (2015)

Development of an In Vitro 3D Model for Investigating Ligamentum Flavum Hypertrophy
por: Lin, Cheng-Li, et al.
Publicado: (2020)

Leptin-induced inflammation by activating IL-6 expression contributes to the fibrosis and hypertrophy of ligamentum flavum in lumbar spinal canal stenosis
por: Sun, Chao, et al.
Publicado: (2018)

Ligamentum flavum analysis in patients with lumbar discus hernia and lumbar spinal stenosis
por: Aleksić, Vuk, et al.
Publicado: (2023)

Spinal Cord Kinking in Thoracic Myelopathy Caused by Ossification of the Ligamentum Flavum
por: Wang, Ting, et al.
Publicado: (2015)

CCN5 Reduces Ligamentum Flavum Hypertrophy by Modulating the TGF‐β Pathway
por: Ye, Sunghyeok, et al.
Publicado: (2019)

An in vivo model of ligamentum flavum hypertrophy from early‐stage inflammation to fibrosis
por: Burt, Kevin G., et al.
Publicado: (2023)

Treatment for lumbar spinal stenosis secondary to ligamentum flavum hypertrophy using percutaneous endoscopy through interlaminar approach: a retrospective study
por: Liu, Yi, et al.
Publicado: (2020)

First report of perforation of ligamentum flavum by sequestrated lumbar intervertebral disc
por: Ozdemir, Bulent, et al.
Publicado: (2017)

Histopathological Analysis of Ligamentum Flavum in Lumbar Spinal Stenosis and Disc Herniation
por: Altun, Idiris, et al.
Publicado: (2017)

Focal Ligamentum Flavum Hypertrophy with Ochronotic Deposits: An Unusual Cause for Neurogenic Claudication in Alkaptonuria
por: Reddy, Rajesh, et al.
Publicado: (2012)

The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy
por: Hu, Wei, et al.
Publicado: (2019)

Identification and validation of hub genes and pathways associated with mitochondrial dysfunction in hypertrophy of ligamentum flavum
por: Gu, Yifei, et al.
Publicado: (2023)

Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1
por: Wang, Shanxi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_djadstiejulau5tnhdvv3s2nlc