Cargando…

Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil

BACKGROUND AND AIM: Although wild boar hunting activities and the hunting dog trade in the Atlantic Forest and Cerrado biomes of Brazil overlap both with endemic and with non-endemic areas for visceral leishmaniasis, no study to date has focused on Leishmania spp. exposure among hunting dogs and hun...

Descripción completa

Detalles Bibliográficos
Autores principales: Kmetiuk, Louise Bach, de Campos, Monique Paiva, Bach, Renato van Wilpe, Brandão, Ana Pérola Drulla, de Barros-Filho, Ivan Roque, Lipinski, Leandro Cavalcante, Fávero, Giovani Marino, dos Santos, Andrea Pires, Fiqueiredo, Fabiano Borges, Biondo, Alexander Welker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654764/
https://www.ncbi.nlm.nih.gov/pubmed/34903933
http://dx.doi.org/10.14202/vetworld.2021.2735-2738
_version_ 1784611933168599040
author Kmetiuk, Louise Bach
de Campos, Monique Paiva
Bach, Renato van Wilpe
Brandão, Ana Pérola Drulla
de Barros-Filho, Ivan Roque
Lipinski, Leandro Cavalcante
Fávero, Giovani Marino
dos Santos, Andrea Pires
Fiqueiredo, Fabiano Borges
Biondo, Alexander Welker
author_facet Kmetiuk, Louise Bach
de Campos, Monique Paiva
Bach, Renato van Wilpe
Brandão, Ana Pérola Drulla
de Barros-Filho, Ivan Roque
Lipinski, Leandro Cavalcante
Fávero, Giovani Marino
dos Santos, Andrea Pires
Fiqueiredo, Fabiano Borges
Biondo, Alexander Welker
author_sort Kmetiuk, Louise Bach
collection PubMed
description BACKGROUND AND AIM: Although wild boar hunting activities and the hunting dog trade in the Atlantic Forest and Cerrado biomes of Brazil overlap both with endemic and with non-endemic areas for visceral leishmaniasis, no study to date has focused on Leishmania spp. exposure among hunting dogs and hunters. The aim of the present study was to assess the presence of Leishmania spp. antibodies in hunting dogs and hunters in different anthropized areas of two Brazilian biomes. MATERIALS AND METHODS: Blood samples were collected from 170 hunting dogs and 46 hunters between October 2016 and May 2018. The presence of antibodies against Leishmania spp. in hunting dogs was screened through a dual-path platform immunochromatographic test (DPP rapid test; Bio-Manguinhos/Fundação Oswaldo Cruz, Rio de Janeiro, Brazil) and in hunters through an rK39-based rapid immunochromatographic test. Both tests were used in accordance with Brazilian Ministry of Health recommendations. RESULTS: Overall, although antibodies were detected through the immunochromatographic test in 3/170 (0.02%) of these female asymptomatic hunting dogs, all living in anthropized areas of the Atlantic Forest biome in South Brazil, no sample was confirmed through the enzyme-linked immunosorbent assay. All the hunters were non-reactive in the rapid immunochromatographic test. CONCLUSION: Our study on three suspicious hunting dogs has suggested that Leishmania (Leishmania) infantum may circulate both in endemic and non-endemic areas in Brazil. In addition, a high rate of hunting dog replacement due to death and trade may have led to less chance of infection and transmission between animals and between animals and humans, which would corroborate the outcomes reported here. Further studies should be conducted to fully establish whether hunting dogs and hunters may be used as sentinels in other areas endemic for Leishmania spp.
format Online
Article
Text
id pubmed-8654764
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Veterinary World
record_format MEDLINE/PubMed
spelling pubmed-86547642021-12-12 Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil Kmetiuk, Louise Bach de Campos, Monique Paiva Bach, Renato van Wilpe Brandão, Ana Pérola Drulla de Barros-Filho, Ivan Roque Lipinski, Leandro Cavalcante Fávero, Giovani Marino dos Santos, Andrea Pires Fiqueiredo, Fabiano Borges Biondo, Alexander Welker Vet World Research Article BACKGROUND AND AIM: Although wild boar hunting activities and the hunting dog trade in the Atlantic Forest and Cerrado biomes of Brazil overlap both with endemic and with non-endemic areas for visceral leishmaniasis, no study to date has focused on Leishmania spp. exposure among hunting dogs and hunters. The aim of the present study was to assess the presence of Leishmania spp. antibodies in hunting dogs and hunters in different anthropized areas of two Brazilian biomes. MATERIALS AND METHODS: Blood samples were collected from 170 hunting dogs and 46 hunters between October 2016 and May 2018. The presence of antibodies against Leishmania spp. in hunting dogs was screened through a dual-path platform immunochromatographic test (DPP rapid test; Bio-Manguinhos/Fundação Oswaldo Cruz, Rio de Janeiro, Brazil) and in hunters through an rK39-based rapid immunochromatographic test. Both tests were used in accordance with Brazilian Ministry of Health recommendations. RESULTS: Overall, although antibodies were detected through the immunochromatographic test in 3/170 (0.02%) of these female asymptomatic hunting dogs, all living in anthropized areas of the Atlantic Forest biome in South Brazil, no sample was confirmed through the enzyme-linked immunosorbent assay. All the hunters were non-reactive in the rapid immunochromatographic test. CONCLUSION: Our study on three suspicious hunting dogs has suggested that Leishmania (Leishmania) infantum may circulate both in endemic and non-endemic areas in Brazil. In addition, a high rate of hunting dog replacement due to death and trade may have led to less chance of infection and transmission between animals and between animals and humans, which would corroborate the outcomes reported here. Further studies should be conducted to fully establish whether hunting dogs and hunters may be used as sentinels in other areas endemic for Leishmania spp. Veterinary World 2021-10 2021-10-24 /pmc/articles/PMC8654764/ /pubmed/34903933 http://dx.doi.org/10.14202/vetworld.2021.2735-2738 Text en Copyright: © Kmetiuk, et al. https://creativecommons.org/licenses/by/4.0/Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Kmetiuk, Louise Bach
de Campos, Monique Paiva
Bach, Renato van Wilpe
Brandão, Ana Pérola Drulla
de Barros-Filho, Ivan Roque
Lipinski, Leandro Cavalcante
Fávero, Giovani Marino
dos Santos, Andrea Pires
Fiqueiredo, Fabiano Borges
Biondo, Alexander Welker
Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil
title Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil
title_full Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil
title_fullStr Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil
title_full_unstemmed Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil
title_short Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil
title_sort serosurvey of anti-leishmania (leishmania) infantum antibodies in hunting dogs and hunters in brazil
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654764/
https://www.ncbi.nlm.nih.gov/pubmed/34903933
http://dx.doi.org/10.14202/vetworld.2021.2735-2738
work_keys_str_mv AT kmetiuklouisebach serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT decamposmoniquepaiva serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT bachrenatovanwilpe serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT brandaoanaperoladrulla serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT debarrosfilhoivanroque serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT lipinskileandrocavalcante serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT faverogiovanimarino serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT dossantosandreapires serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT fiqueiredofabianoborges serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil
AT biondoalexanderwelker serosurveyofantileishmanialeishmaniainfantumantibodiesinhuntingdogsandhuntersinbrazil