Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m(6)A consensus sequences

Extracellular vesicles (EVs) are capable of transferring cargo from donor to recipient cells, but precisely how cargo content is regulated for export is mostly unknown. For miRNA cargo, we previously showed that when compared to isogenic colorectal cancer (CRC) cells expressing wild-type KRAS, a dis...

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Detalles Bibliográficos
Autores principales: Abner, Jessica J., Franklin, Jeffrey L., Clement, Margaret A., Hinger, Scott A., Allen, Ryan M., Liu, Xiao, Kellner, Stefanie, Wu, Junzhou, Karijolich, John, Liu, Qi, Vickers, Kasey C., Dedon, Peter, Weaver, Alissa M., Coffey, Robert J., Patton, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654799/
https://www.ncbi.nlm.nih.gov/pubmed/34934837
http://dx.doi.org/10.1016/j.heliyon.2021.e08519

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