Cargando…

Hotspots for mutations in the SARS-CoV-2 spike glycoprotein: a correspondence analysis

Spike glycoprotein (Sgp) is liable for binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the host receptors. Since Sgp is the main target for vaccine and drug designing, elucidating its mutation pattern could help in this regard. This study is aimed at investigating the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rahbar, Mohammad Reza, Jahangiri, Abolfazl, Khalili, Saeed, Zarei, Mahboubeh, Mehrabani-Zeinabad, Kamran, Khalesi, Bahman, Pourzardosht, Navid, Hessami, Anahita, Nezafat, Navid, Sadraei, Saman, Negahdaripour, Manica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654821/ https://www.ncbi.nlm.nih.gov/pubmed/34880279 http://dx.doi.org/10.1038/s41598-021-01655-y

Ejemplares similares

Pierce into Structural Changes of Interactions Between Mutated Spike Glycoproteins and ACE2 to Evaluate Its Potential Biological and Therapeutic Consequences
por: Hashemi, Zahra Sadat, et al.
Publicado: (2021)

A unique antigen against SARS-CoV-2, Acinetobacter baumannii, and Pseudomonas aeruginosa
por: Rahbar, Mohammad Reza, et al.
Publicado: (2022)

Non-adaptive Evolution of Trimeric Autotransporters in Brucellaceae
por: Rahbar, Mohammad Reza, et al.
Publicado: (2020)

In silico Approaches for the Design and Optimization of Interfering Peptides Against Protein–Protein Interactions
por: Hashemi, Zahra Sadat, et al.
Publicado: (2021)

SARS-CoV-2 Proteome Harbors Peptides Which Are Able to Trigger Autoimmunity Responses: Implications for Infection, Vaccination, and Population Coverage
por: Karami Fath, Mohsen, et al.
Publicado: (2021)

In silico design and evaluation of a novel mRNA vaccine against BK virus: a reverse vaccinology approach
por: Mohammadi, Yasaman, et al.
Publicado: (2022)

Harnessing self-assembled peptide nanoparticles in epitope vaccine design
por: Negahdaripour, Manica, et al.
Publicado: (2017)

Impact of SNPs, off-targets, and passive permeability on efficacy of BCL6 degrading drugs assigned by virtual screening and 3D-QSAR approach
por: Karimi, Solmaz, et al.
Publicado: (2022)

Optimization of Three Dimensional Culturing of the HepG2 Cell Line in Fibrin Scaffold
por: Banihashemi, Mehrzad, et al.
Publicado: (2015)

Molecular mechanisms and therapeutic effects of different vitamins and minerals in COVID-19 patients
por: Fath, Mohsen Karami, et al.
Publicado: (2022)

Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms
por: Karami Fath, Mohsen, et al.
Publicado: (2022)

Theta-Defensins to Counter COVID-19 as Furin Inhibitors: In Silico Efficiency Prediction and Novel Compound Design
por: Negahdaripour, Manica, et al.
Publicado: (2022)

An Efficient and Effective Model to Handle Missing Data in Classification
por: Mehrabani-Zeinabad, Kamran, et al.
Publicado: (2020)

Exosome-based strategies for diagnosis and therapy of glioma cancer
por: Karami Fath, Mohsen, et al.
Publicado: (2022)

Response Surface Methodology to Optimize the Expression Efficiency of Recombinant Reteplase
por: Farzaneh, Farhad, et al.
Publicado: (2023)

Enhanced hyluronic acid production in Streptococcus zooepidemicus by over expressing HasA and molecular weight control with Niscin and glucose
por: Zakeri, Alireza, et al.
Publicado: (2017)

The Rise and Fall in Therapeutic Candidates for COVID-19
por: Negahdaripour, Manica
Publicado: (2020)

The Battle Against COVID-19: Where Do We Stand Now?
por: Negahdaripour, Manica
Publicado: (2020)

A World of Changes: The Inheritance of COVID-19
por: Negahdaripour, Manica
Publicado: (2020)

Fifty Years of Witnessing Biomedical Science Developments
por: Negahdaripour, Manica
Publicado: (2020)

COVID-19 Vaccine Global Access Is an Urgency
por: Negahdaripour, Manica
Publicado: (2021)

Post-COVID-19 Hyperglycemia: A Concern in Selection of Therapeutic Regimens
por: Negahdaripour, Manica
Publicado: (2021)

Photocatalytic activity of ZrO(2)/TiO(2)/Fe(3)O(4) ternary nanocomposite for the degradation of naproxen: characterization and optimization using response surface methodology
por: Zare, Masoud Habibi, et al.
Publicado: (2022)

Yolk@Wrinkled-double shell smart nanoreactors: new platforms for mineralization of pharmaceutical wastewater
por: Habibi Zare, Masoud, et al.
Publicado: (2023)

Cardiovascular disease incidence prediction by machine learning and statistical techniques: a 16-year cohort study from eastern Mediterranean region
por: Mehrabani-Zeinabad, Kamran, et al.
Publicado: (2023)

Role of Cultured Skin Fibroblasts in Aesthetic and Plastic Surgery
por: Mehrabani, Davood, et al.
Publicado: (2013)

Evaluation of Recombinant Human Growth Hormone Secretion in E. coli using the L-asparaginase II Signal Peptide
por: Zamani, Mozhdeh, et al.
Publicado: (2016)

Immunotherapeutic approaches to curtail COVID-19
por: Owji, Hajar, et al.
Publicado: (2020)

Deep survey for designing a vaccine against SARS-CoV-2 and its new mutations
por: Vakili, Bahareh, et al.
Publicado: (2021)

Iranian Journal of Medical Sciences: 2021 Review and 2022 Outlook
por: Mahdiyar, Zahra, et al.
Publicado: (2022)

Current understanding of epigenetics role in melanoma treatment and resistance
por: Karami Fath, Mohsen, et al.
Publicado: (2022)

Editorial: Recent advances in the development of vaccines against Acinetobacter baumannii
por: Khalili, Saeed, et al.
Publicado: (2023)

Design of an engineered ACE2 as a novel therapeutics against COVID-19
por: Payandeh, Zahra, et al.
Publicado: (2020)

Single-bubble EHD behavior into water two-phase flow under electric-field stress and gravitational acceleration using PFM
por: Mianmahale, Maryam Aliakbary, et al.
Publicado: (2021)

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
por: Karami, Forough, et al.
Publicado: (2019)

Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation
por: Poustforoosh, Alireza, et al.
Publicado: (2023)

Identification of a Novel Splice Site Mutation in RUNX2 Gene in a Family with Rare Autosomal Dominant Cleidocranial Dysplasia
por: Jamali, Ebrahim, et al.
Publicado: (2021)

Designing self-assembled peptide nanovaccine against Streptococcus pneumoniae: An in silico strategy
por: Dorosti, Hesam, et al.
Publicado: (2019)

Impact of diabesity phenotype on cardiovascular diseases, major cardiovascular events and all-cause mortality
por: Mehrabani-Zeinabad, Kamran, et al.
Publicado: (2023)

Harnessing the non-specific immunogenic effects of available vaccines to combat COVID-19
por: Mosaddeghi, Pouria, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hl2o4flb43u5jf8j9jttl3mfj1