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Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling
Protein domains are the basic units of protein structure and function. Comparative analysis of genomes and proteomes showed that domain recombination is a main driver of multidomain protein functional diversification and some of the constraining genomic mechanisms are known. Much less is known about...
Autores principales: | Coyote-Maestas, Willow, Nedrud, David, Suma, Antonio, He, Yungui, Matreyek, Kenneth A., Fowler, Douglas M., Carnevale, Vincenzo, Myers, Chad L., Schmidt, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654947/ https://www.ncbi.nlm.nih.gov/pubmed/34880224 http://dx.doi.org/10.1038/s41467-021-27342-0 |
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