GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1

Activation of thermogenic brown and beige adipocytes is considered as a strategy to improve metabolic control. Here, we identify GPR180 as a receptor regulating brown and beige adipocyte function and whole-body glucose homeostasis, whose expression in humans is associated with improved metabolic con...

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Detalles Bibliográficos
Autores principales: Balazova, Lucia, Balaz, Miroslav, Horvath, Carla, Horváth, Áron, Moser, Caroline, Kovanicova, Zuzana, Ghosh, Adhideb, Ghoshdastider, Umesh, Efthymiou, Vissarion, Kiehlmann, Elke, Sun, Wenfei, Dong, Hua, Ding, Lianggong, Amri, Ez-Zoubir, Nuutila, Pirjo, Virtanen, Kirsi A., Niemi, Tarja, Ukropcova, Barbara, Ukropec, Jozef, Pelczar, Pawel, Lamla, Thorsten, Hamilton, Bradford, Neubauer, Heike, Wolfrum, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655035/
https://www.ncbi.nlm.nih.gov/pubmed/34880217
http://dx.doi.org/10.1038/s41467-021-27442-x

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