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Post-translational modifications by SIRT3 de-2-hydroxyisobutyrylase activity regulate glycolysis and enable nephrogenesis

Abnormal kidney development leads to lower nephron number, predisposing to renal diseases in adulthood. In embryonic kidneys, nephron endowment is dictated by the availability of nephron progenitors, whose self-renewal and differentiation require a relatively repressed chromatin state. More recently...

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Detalles Bibliográficos
Autores principales:	Perico, Luca, Morigi, Marina, Pezzotta, Anna, Corna, Daniela, Brizi, Valerio, Conti, Sara, Zanchi, Cristina, Sangalli, Fabio, Trionfini, Piera, Buttò, Sara, Xinaris, Christodoulos, Tomasoni, Susanna, Zoja, Carlamaria, Remuzzi, Giuseppe, Benigni, Ariela, Imberti, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655075/ https://www.ncbi.nlm.nih.gov/pubmed/34880332 http://dx.doi.org/10.1038/s41598-021-03039-8

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