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Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes

Laminin-332 pemphigoid is a rare and severe autoimmune blistering disease, caused by IgG autoantibodies targeting laminin-332 in the dermal-epidermal basement zone. Laminin-332 pemphigoid is characterized by variable inflammatory infiltrate and the predominance of non-complement-fixing antibodies. G...

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Detalles Bibliográficos
Autores principales:	Bao, Lei, Li, Jing, Solimani, Farzan, Didona, Dario, Patel, Payal M., Li, Xiaoguang, Qian, Hua, Ishii, Norito, Hashimoto, Takashi, Hertl, Michael, Amber, Kyle T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655097/ https://www.ncbi.nlm.nih.gov/pubmed/34899732 http://dx.doi.org/10.3389/fimmu.2021.775412

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