Interferon Lambda Signaling in Macrophages Is Necessary for the Antiviral Response to Influenza

Interferon lambda (IFNλ) signaling is a promising therapeutic target against viral infection in murine models, yet little is known about its molecular regulation and its cognate receptor, interferon lambda receptor 1 (IFNLR1) in human lung. We hypothesized that the IFNλ signaling axis was active in...

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Detalles Bibliográficos
Autores principales: Mallampalli, Rama K., Adair, Jessica, Elhance, Ajit, Farkas, Daniela, Chafin, Lexie, Long, Matthew E., De, Mithu, Mora, Ana L., Rojas, Mauricio, Peters, Victor, Bednash, Joseph S., Tsai, MuChun, Londino, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655102/
https://www.ncbi.nlm.nih.gov/pubmed/34899695
http://dx.doi.org/10.3389/fimmu.2021.735576

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