Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease

INTRODUCTION: Alzheimer’s disease (AD) is a progressive brain disorder, and one of the most common causes of dementia and amnesia. Due to the complex pathogenesis of AD, the underlying mechanisms remain unclear. Although scientists have made increasing efforts to develop drugs for AD, no effective t...

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Detalles Bibliográficos
Autores principales: Bian, Yaqi, Chen, Yan, Wang, Xiufen, Cui, Guozhen, Ung, Carolina Oi Lam, Lu, Jia-Hong, Cong, Weihong, Tang, Benqin, Lee, Simon Ming-Yuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655137/
https://www.ncbi.nlm.nih.gov/pubmed/35024177
http://dx.doi.org/10.1016/j.jare.2021.09.002

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