Cargando…

Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides

The fragile histidine triad (FHIT) protein is a member of the large and ubiquitous histidine triad (HIT) family of proteins. On the basis of genetic evidence, it has been postulated that the FHIT protein may function as tumor suppressor, implying a role for the FHIT protein in carcinogenesis. Recent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scala, Maria Carmina, Di Micco, Simone, Lanzillotta, Delia, Musella, Simona, Di Sarno, Veronica, Parrino, Barbara, Cascioferro, Stella Maria, Bifulco, Giuseppe, Trapasso, Francesco, Campiglia, Pietro, Sala, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655160/ https://www.ncbi.nlm.nih.gov/pubmed/34901149 http://dx.doi.org/10.3389/fmolb.2021.715263

Ejemplares similares

Corrigendum: Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides
por: Scala, Maria Carmina, et al.
Publicado: (2022)

The Fhit protein: an opportunity to overcome chemoresistance
por: Gaudio, Eugenio, et al.
Publicado: (2016)

A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells
por: Gaudio, Eugenio, et al.
Publicado: (2016)

In silico Analysis Revealed Potential Anti-SARS-CoV-2 Main Protease Activity by the Zonulin Inhibitor Larazotide Acetate
por: Di Micco, Simone, et al.
Publicado: (2021)

Overcoming Chemoresistance via Extracellular Vesicle Inhibition
por: Hayatudin, Raeesah, et al.
Publicado: (2021)

Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation
por: Di Micco, Simone, et al.
Publicado: (2021)

New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity
por: Cascioferro, Stella, et al.
Publicado: (2019)

Discovery of a Novel Tetrapeptide against Influenza A Virus: Rational Design, Synthesis, Bioactivity Evaluation and Computational Studies
por: Scala, Maria Carmina, et al.
Publicado: (2021)

Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors
por: Scala, Maria Carmina, et al.
Publicado: (2017)

Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization
por: Di Sarno, Veronica, et al.
Publicado: (2021)

Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor
por: Musella, Simona, et al.
Publicado: (2016)

The Tumour Suppressor Fhit Protein Activates C-Raf Ubiquitination and Degradation in Human Melanoma Cells by Interacting with Hsp90
por: Paduano, Francesco, et al.
Publicado: (2022)

Dipropyleneglycol Dimethylether, New Green Solvent for Solid-Phase Peptide Synthesis: Further Challenges to Improve Sustainability in the Development of Therapeutic Peptides
por: Vivenzio, Giovanni, et al.
Publicado: (2023)

Rational Design of Novel Peptidomimetics against Influenza A Virus: Biological and Computational Studies
por: Scala, Maria Carmina, et al.
Publicado: (2023)

Restored expression of Fhit protein in Fhit-minus breast cancer cells
por: Campiglio, M, et al.
Publicado: (2001)

Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2
por: Di Micco, Simone, et al.
Publicado: (2022)

FHIT gene and cancer.
Publicado: (1996)

Editorial: Biophysics of co-translational protein folding
por: Fried, Stephen D., et al.
Publicado: (2022)

Biophysical Screening Pipeline for Cryo-EM Grid Preparation of Membrane Proteins
por: Niebling, Stephan, et al.
Publicado: (2022)

Comparison of hydrophobicity scales for predicting biophysical properties of antibodies
por: Waibl, Franz, et al.
Publicado: (2022)

Editorial: Intersection of biophysical and structural approaches in vaccine design
por: Ptak, Christopher P., et al.
Publicado: (2023)

Editorial: Insights in protein biochemistry: protein biophysics 2022
por: Labrou, Nikolaos E., et al.
Publicado: (2023)

Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy
por: Parrino, Barbara, et al.
Publicado: (2018)

Antiviral Peptides as Anti-Influenza Agents
por: Agamennone, Mariangela, et al.
Publicado: (2022)

The Proton in Biochemistry: Impacts on Bioenergetics, Biophysical Chemistry, and Bioorganic Chemistry
por: Silverstein, Todd P.
Publicado: (2021)

Revitalizing an important field in biophysics: The new frontiers of molecular crowding
por: Cammarata, Marco, et al.
Publicado: (2023)

Extracellular Vesicle-Mediated Chemoresistance in Oral Squamous Cell Carcinoma
por: Law, Zhu-Jun, et al.
Publicado: (2021)

FHIT Doubts are Clear Now
por: Wali, Anjilna
Publicado: (2010)

Targeting Cancer Stem Cells to Overcome Chemoresistance
por: Nunes, Toni, et al.
Publicado: (2018)

SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance
por: Randazzo, Ornella, et al.
Publicado: (2021)

Measuring Protein Aggregation and Stability Using High-Throughput Biophysical Approaches
por: Kwan, Tristan O. C., et al.
Publicado: (2022)

Pilot study on the influence of acute alcohol exposure on biophysical parameters of leukocytes
por: Shalchi-Amirkhiz, Puya, et al.
Publicado: (2023)

Contemporary biophysical approaches for studying 14-3-3 protein-protein interactions
por: Thurairajah, Bethany, et al.
Publicado: (2022)

Synthesis and Ex Vivo Trans-Corneal Permeation of Penetratin Analogues as Ophthalmic Carriers: Preliminary Results
por: Pescina, Silvia, et al.
Publicado: (2020)

Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells
por: Druck, Teresa, et al.
Publicado: (2019)

Recent Developments in the Inhibition of Bacterial Adhesion as Promising Anti-Virulence Strategy
por: Pecoraro, Camilla, et al.
Publicado: (2023)

Structure-Based Development of SARS-CoV-2 Spike Interactors
por: Squeglia, Flavia, et al.
Publicado: (2022)

Aberrant FHIT transcripts in hepatocellular carcinomas.
por: Chen, Y. J., et al.
Publicado: (1998)

The Role of Notch3 Signaling in Cancer Stemness and Chemoresistance: Molecular Mechanisms and Targeting Strategies
por: Xiu, Mengxi, et al.
Publicado: (2021)

Association of FHIT expression and FHIT gene hypermethylation with liver cancer risk: a PRISMA-compliant meta-analysis
por: Zhang, Yaping, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lsbm0qg9tpk1ma0050ajbornqa