Inhibition of the PLK1‐Coupled Cell Cycle Machinery Overcomes Resistance to Oxaliplatin in Colorectal Cancer

Dysregulation of the cell cycle machinery leads to genomic instability and is a hallmark of cancer associated with chemoresistance and poor prognosis in colorectal cancer (CRC). Identifying and targeting aberrant cell cycle machinery is expected to improve current therapies for CRC patients. Here,up...

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Detalles Bibliográficos
Autores principales: Yu, Zhaoliang, Deng, Peng, Chen, Yufeng, Liu, Shini, Chen, Jinghong, Yang, Zihuan, Chen, Jianfeng, Fan, Xinjuan, Wang, Peili, Cai, Zerong, Wang, Yali, Hu, Peishan, Lin, Dezheng, Xiao, Rong, Zou, Yifeng, Huang, Yan, Yu, Qiang, Lan, Ping, Tan, Jing, Wu, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655181/
https://www.ncbi.nlm.nih.gov/pubmed/34881526
http://dx.doi.org/10.1002/advs.202100759

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