A synonymous mutation in IGF-1 impacts the transcription and translation process of gene expression

Insulin-like growth factor 1 (IGF-1) is considered to be a crucial gene in the animal development of bone and body size. In this study, a unique synonymous mutation (c.258 A > G) of the IGF-1 gene was modified with an adenine base editor to observe the growth and developmental situation of mutant...

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Detalles Bibliográficos
Autores principales: Wang, S.Y., Cheng, Y.Y., Liu, S.C., Xu, Y.X., Gao, Y., Wang, C.L., Wang, Z.G., Feng, T.Q., Lu, G.H., Song, J., Xia, P.J., Hao, L.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655398/
https://www.ncbi.nlm.nih.gov/pubmed/34938600
http://dx.doi.org/10.1016/j.omtn.2021.08.007

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