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Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic

BACKGROUND: Due to the social isolation measures adopted in an attempt to mitigate the risk of transmission of SARS-CoV-2, there has been a reduction in vaccination coverage of children and adolescents in several countries and regions of the world. OBJECTIVE: Analyze the number of doses of vaccine a...

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Autores principales: da Silva, Tércia Moreira Ribeiro, de Sá, Ana Carolina Micheletti Gomide Nogueira, Vieira, Ed Wilson Rodrigues, Prates, Elton Junio Sady, Beinner, Mark Anthony, Matozinhos, Fernanda Penido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655492/
https://www.ncbi.nlm.nih.gov/pubmed/34886804
http://dx.doi.org/10.1186/s12879-021-06927-6
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author da Silva, Tércia Moreira Ribeiro
de Sá, Ana Carolina Micheletti Gomide Nogueira
Vieira, Ed Wilson Rodrigues
Prates, Elton Junio Sady
Beinner, Mark Anthony
Matozinhos, Fernanda Penido
author_facet da Silva, Tércia Moreira Ribeiro
de Sá, Ana Carolina Micheletti Gomide Nogueira
Vieira, Ed Wilson Rodrigues
Prates, Elton Junio Sady
Beinner, Mark Anthony
Matozinhos, Fernanda Penido
author_sort da Silva, Tércia Moreira Ribeiro
collection PubMed
description BACKGROUND: Due to the social isolation measures adopted in an attempt to mitigate the risk of transmission of SARS-CoV-2, there has been a reduction in vaccination coverage of children and adolescents in several countries and regions of the world. OBJECTIVE: Analyze the number of doses of vaccine against Measles-Mumps-Rubella (MMR) applied before and after the beginning of mitigation measures due to COVID-19 pandemic in Brazil. METHODS: The data collected refer to the number of doses of the MMR vaccine applied monthly to the target population residing in Brazil: cahildren, aged 12 months (first dose) and children, aged 9 years (second dose), from April 2019 to December 2020. Differences in MMR vaccine doses from April 2019 to March 2020 (before the start of mitigation measures) and April 2020 to September 2020 (after the start of the mitigation measures) were evaluated. Spatial analysis identified clusters with a high percentage of reduction in the median of applied doses no Brazil. RESULTS: There was a reduction in the median of doses applied in the Regions North (− 33.03%), Northeast (− 43.49%) and South (− 39.01%) e nos Estados Acre (− 48.46%), Amazonas (− 28.96%), Roraima (− 61.91%), Paraíba (− 41.58%), Sergipe (− 47.52%), Rio de Janeiro (-59.31%) and Santa Catarina (− 49.32) (p < 0.05). High-high type spatial clusters (reduction between 34.00 and 90.00%) were formed in the five regions of Brazil (Moran’s I = 0.055; p = 0.01). CONCLUSION: A reduction in the number of MMR vaccine doses was evidenced as a possible effect by the restrictive actions of COVID-19 in Brazil.
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spelling pubmed-86554922021-12-09 Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic da Silva, Tércia Moreira Ribeiro de Sá, Ana Carolina Micheletti Gomide Nogueira Vieira, Ed Wilson Rodrigues Prates, Elton Junio Sady Beinner, Mark Anthony Matozinhos, Fernanda Penido BMC Infect Dis Research BACKGROUND: Due to the social isolation measures adopted in an attempt to mitigate the risk of transmission of SARS-CoV-2, there has been a reduction in vaccination coverage of children and adolescents in several countries and regions of the world. OBJECTIVE: Analyze the number of doses of vaccine against Measles-Mumps-Rubella (MMR) applied before and after the beginning of mitigation measures due to COVID-19 pandemic in Brazil. METHODS: The data collected refer to the number of doses of the MMR vaccine applied monthly to the target population residing in Brazil: cahildren, aged 12 months (first dose) and children, aged 9 years (second dose), from April 2019 to December 2020. Differences in MMR vaccine doses from April 2019 to March 2020 (before the start of mitigation measures) and April 2020 to September 2020 (after the start of the mitigation measures) were evaluated. Spatial analysis identified clusters with a high percentage of reduction in the median of applied doses no Brazil. RESULTS: There was a reduction in the median of doses applied in the Regions North (− 33.03%), Northeast (− 43.49%) and South (− 39.01%) e nos Estados Acre (− 48.46%), Amazonas (− 28.96%), Roraima (− 61.91%), Paraíba (− 41.58%), Sergipe (− 47.52%), Rio de Janeiro (-59.31%) and Santa Catarina (− 49.32) (p < 0.05). High-high type spatial clusters (reduction between 34.00 and 90.00%) were formed in the five regions of Brazil (Moran’s I = 0.055; p = 0.01). CONCLUSION: A reduction in the number of MMR vaccine doses was evidenced as a possible effect by the restrictive actions of COVID-19 in Brazil. BioMed Central 2021-12-09 /pmc/articles/PMC8655492/ /pubmed/34886804 http://dx.doi.org/10.1186/s12879-021-06927-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
da Silva, Tércia Moreira Ribeiro
de Sá, Ana Carolina Micheletti Gomide Nogueira
Vieira, Ed Wilson Rodrigues
Prates, Elton Junio Sady
Beinner, Mark Anthony
Matozinhos, Fernanda Penido
Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic
title Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic
title_full Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic
title_fullStr Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic
title_full_unstemmed Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic
title_short Number of doses of Measles-Mumps-Rubella vaccine applied in Brazil before and during the COVID-19 pandemic
title_sort number of doses of measles-mumps-rubella vaccine applied in brazil before and during the covid-19 pandemic
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655492/
https://www.ncbi.nlm.nih.gov/pubmed/34886804
http://dx.doi.org/10.1186/s12879-021-06927-6
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