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Stimulation of the Runx2 P1 promoter by collagen-derived dipeptide prolyl-hydroxyproline bound to Foxg1 and Foxo1 in osteoblasts
Collagen-derived dipeptide prolyl-hydroxyproline (Pro-Hyp) directly binds to the forkhead box g1 (Foxg1) protein and causes it to undergo structural alteration. Pro-Hyp also promotes the production of a regulator of osteoblast differentiation, Runt-related transcription factor 2 (Runx2), through Fox...
Autores principales: | Nomura, Kaho, Kimira, Yoshifumi, Osawa, Yoshihiro, Kataoka-Matsushita, Aya, Takao, Koichi, Sugita, Yoshiaki, Shimizu, Jun, Wada, Masahiro, Mano, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655505/ https://www.ncbi.nlm.nih.gov/pubmed/34779485 http://dx.doi.org/10.1042/BSR20210304 |
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