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Safety and tolerability of a single infusion of autologous ex vivo expanded regulatory T cells in adults with ulcerative colitis (ER-TREG 01): protocol of a phase 1, open-label, fast-track dose-escalation clinical trial

INTRODUCTION: Accumulating evidence suggests that the adoptive transfer of ex vivo expanded regulatory T cells (Treg) may overcome colitogenic immune responses in patients with inflammatory bowel diseases. The objective of the ER-TREG 01 trial is to assess safety and tolerability of a single infusio...

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Detalles Bibliográficos
Autores principales:	Voskens, Caroline J, Stoica, Diane, Roessner, Susanne, Vitali, Francesco, Zundler, Sebastian, Rosenberg, Marita, Wiesinger, Manuel, Wunder, Jutta, Siegmund, Britta, Schuler-Thurner, Beatrice, Schuler, Gerold, Berking, Carola, Atreya, Raja, Neurath, Markus F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Gastroenterology and Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655533/ https://www.ncbi.nlm.nih.gov/pubmed/34880013 http://dx.doi.org/10.1136/bmjopen-2021-049208

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