Cargando…
Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)
Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 8...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655623/ https://www.ncbi.nlm.nih.gov/pubmed/34934460 http://dx.doi.org/10.2903/j.efsa.2021.6982 |
_version_ | 1784612112530669568 |
---|---|
author | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Fašmon Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Edoardo Villa, Roberto Woutersen, Ruud Galobart, Jaume Manini, Paola Pettenati, Elisa Tarrés Call, Jordi Anguita, Montserrat |
author_facet | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Fašmon Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Edoardo Villa, Roberto Woutersen, Ruud Galobart, Jaume Manini, Paola Pettenati, Elisa Tarrés Call, Jordi Anguita, Montserrat |
collection | PubMed |
description | Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 80187 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified and viable cells of the production strain, and its DNA were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. Monosodium l‐glutamate monohydrate produced using C. glutamicum KCCM 80187 is considered safe for the target species, for the consumer and for the environment. Moreover, it is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed. |
format | Online Article Text |
id | pubmed-8655623 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86556232021-12-20 Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Fašmon Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Edoardo Villa, Roberto Woutersen, Ruud Galobart, Jaume Manini, Paola Pettenati, Elisa Tarrés Call, Jordi Anguita, Montserrat EFSA J Scientific Opinion Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 80187 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified and viable cells of the production strain, and its DNA were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. Monosodium l‐glutamate monohydrate produced using C. glutamicum KCCM 80187 is considered safe for the target species, for the consumer and for the environment. Moreover, it is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed. John Wiley and Sons Inc. 2021-12-09 /pmc/articles/PMC8655623/ /pubmed/34934460 http://dx.doi.org/10.2903/j.efsa.2021.6982 Text en © 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Fašmon Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Edoardo Villa, Roberto Woutersen, Ruud Galobart, Jaume Manini, Paola Pettenati, Elisa Tarrés Call, Jordi Anguita, Montserrat Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) |
title | Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) |
title_full | Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) |
title_fullStr | Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) |
title_full_unstemmed | Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) |
title_short | Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) |
title_sort | safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with corynebacterium glutamicum kccm 80187 for all animal species (cj europe gmbh) |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655623/ https://www.ncbi.nlm.nih.gov/pubmed/34934460 http://dx.doi.org/10.2903/j.efsa.2021.6982 |
work_keys_str_mv | AT safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT bampidisvasileios safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT azimontigiovanna safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT bastosmariadelourdes safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT christensenhenrik safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT dusemundbirgit safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT fasmondurjavamojca safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT koubamaryline safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT lopezalonsomarta safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT lopezpuentesecundino safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT marconfrancesca safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT mayobaltasar safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT pechovaalena safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT petkovamariana safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT ramosfernando safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT sanzyolanda safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT edoardovillaroberto safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT woutersenruud safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT galobartjaume safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT maninipaola safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT pettenatielisa safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT tarrescalljordi safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh AT anguitamontserrat safetyandefficacyofafeedadditiveconsistingofmonosodiumlglutamateproducedbyfermentationwithcorynebacteriumglutamicumkccm80187forallanimalspeciescjeuropegmbh |