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Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)

Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 8...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Fašmon Durjava, Mojca, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Edoardo Villa, Roberto, Woutersen, Ruud, Galobart, Jaume, Manini, Paola, Pettenati, Elisa, Tarrés Call, Jordi, Anguita, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655623/
https://www.ncbi.nlm.nih.gov/pubmed/34934460
http://dx.doi.org/10.2903/j.efsa.2021.6982
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Edoardo Villa, Roberto
Woutersen, Ruud
Galobart, Jaume
Manini, Paola
Pettenati, Elisa
Tarrés Call, Jordi
Anguita, Montserrat
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Edoardo Villa, Roberto
Woutersen, Ruud
Galobart, Jaume
Manini, Paola
Pettenati, Elisa
Tarrés Call, Jordi
Anguita, Montserrat
collection PubMed
description Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 80187 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified and viable cells of the production strain, and its DNA were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. Monosodium l‐glutamate monohydrate produced using C. glutamicum KCCM 80187 is considered safe for the target species, for the consumer and for the environment. Moreover, it is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed.
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spelling pubmed-86556232021-12-20 Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH) Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Fašmon Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Edoardo Villa, Roberto Woutersen, Ruud Galobart, Jaume Manini, Paola Pettenati, Elisa Tarrés Call, Jordi Anguita, Montserrat EFSA J Scientific Opinion Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 80187 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified and viable cells of the production strain, and its DNA were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. Monosodium l‐glutamate monohydrate produced using C. glutamicum KCCM 80187 is considered safe for the target species, for the consumer and for the environment. Moreover, it is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed. John Wiley and Sons Inc. 2021-12-09 /pmc/articles/PMC8655623/ /pubmed/34934460 http://dx.doi.org/10.2903/j.efsa.2021.6982 Text en © 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Edoardo Villa, Roberto
Woutersen, Ruud
Galobart, Jaume
Manini, Paola
Pettenati, Elisa
Tarrés Call, Jordi
Anguita, Montserrat
Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)
title Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)
title_full Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)
title_fullStr Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)
title_full_unstemmed Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)
title_short Safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with Corynebacterium glutamicum KCCM 80187 for all animal species (CJ Europe GmbH)
title_sort safety and efficacy of a feed additive consisting of monosodium l‐glutamate produced by fermentation with corynebacterium glutamicum kccm 80187 for all animal species (cj europe gmbh)
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655623/
https://www.ncbi.nlm.nih.gov/pubmed/34934460
http://dx.doi.org/10.2903/j.efsa.2021.6982
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