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Chronic Hematuria Increases Chronic Kidney Injury and Epithelial–Mesenchymal Transition in 5/6 Nephrectomy Rats

Chronic kidney disease (CKD) is a common outcome of many kidney diseases. Interstitial fibrosis and tubular atrophy (IFTA) is a histologic hallmark of CKD. Hematuria is a common symptom in many human kidney diseases. Free hemoglobin may affect tubular epithelial cells by generating reactive oxygen s...

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Detalles Bibliográficos
Autores principales: Xiao, Min, Medipally, Ajay K., Biederman, Laura, Satoskar, Anjali A., Ivanov, Iouri, Rovin, Brad H., Brodsky, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655688/
https://www.ncbi.nlm.nih.gov/pubmed/34901065
http://dx.doi.org/10.3389/fmed.2021.753506