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Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report

Although endometrial cancer is extremely rare during pregnancy, the placental metastasis of endometrial cancer is even rarer. The current study presents a case of endometrial carcinoma that was diagnosed through the pathological examination of the placenta. A 35-year-old primipara woman who underwen...

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Autores principales: Maeda, Takaaki, Nishimura, Masato, Sogawa, Eishi, Kaji, Takashi, Irahara, Minoru, Iwasa, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655730/
https://www.ncbi.nlm.nih.gov/pubmed/34909202
http://dx.doi.org/10.3892/mco.2021.2457
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author Maeda, Takaaki
Nishimura, Masato
Sogawa, Eishi
Kaji, Takashi
Irahara, Minoru
Iwasa, Takeshi
author_facet Maeda, Takaaki
Nishimura, Masato
Sogawa, Eishi
Kaji, Takashi
Irahara, Minoru
Iwasa, Takeshi
author_sort Maeda, Takaaki
collection PubMed
description Although endometrial cancer is extremely rare during pregnancy, the placental metastasis of endometrial cancer is even rarer. The current study presents a case of endometrial carcinoma that was diagnosed through the pathological examination of the placenta. A 35-year-old primipara woman who underwent frozen-thawed embryo transfer at the Keiai Ladies Clinic in Tokushima prefecture (Japan) received regular prenatal check-ups. She was transferred to Tokushima University Hospital for perinatal management due to the preterm premature rupture of membranes at 21 weeks and 6 days gestation. The administration of antibiotics and tocolytic agents was continued; however, labor pain occurred at 23 weeks and 3 days gestation, and a female fetus weighing 524 g was delivered vaginally. The placenta weighed 262 g and had no macroscopic abnormalities. It was submitted for pathological examination, which revealed metastatic adenocarcinoma (clear cell carcinoma suspected). The patient was subsequently diagnosed with endometrial cancer (stage I suspected), and underwent abdominal total hysterectomy, bilateral salpingo-oophorectomy, partial omentectomy and pelvic lymph node dissection. The final diagnosis was stage IA endometrial cancer (endometrioid carcinoma, G2). At 1 year after surgery, there was no evidence of disease. The present case highlights the importance of considering the emergence of endometrial cancer during pregnancy.
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spelling pubmed-86557302021-12-13 Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report Maeda, Takaaki Nishimura, Masato Sogawa, Eishi Kaji, Takashi Irahara, Minoru Iwasa, Takeshi Mol Clin Oncol Articles Although endometrial cancer is extremely rare during pregnancy, the placental metastasis of endometrial cancer is even rarer. The current study presents a case of endometrial carcinoma that was diagnosed through the pathological examination of the placenta. A 35-year-old primipara woman who underwent frozen-thawed embryo transfer at the Keiai Ladies Clinic in Tokushima prefecture (Japan) received regular prenatal check-ups. She was transferred to Tokushima University Hospital for perinatal management due to the preterm premature rupture of membranes at 21 weeks and 6 days gestation. The administration of antibiotics and tocolytic agents was continued; however, labor pain occurred at 23 weeks and 3 days gestation, and a female fetus weighing 524 g was delivered vaginally. The placenta weighed 262 g and had no macroscopic abnormalities. It was submitted for pathological examination, which revealed metastatic adenocarcinoma (clear cell carcinoma suspected). The patient was subsequently diagnosed with endometrial cancer (stage I suspected), and underwent abdominal total hysterectomy, bilateral salpingo-oophorectomy, partial omentectomy and pelvic lymph node dissection. The final diagnosis was stage IA endometrial cancer (endometrioid carcinoma, G2). At 1 year after surgery, there was no evidence of disease. The present case highlights the importance of considering the emergence of endometrial cancer during pregnancy. D.A. Spandidos 2022-01 2021-12-01 /pmc/articles/PMC8655730/ /pubmed/34909202 http://dx.doi.org/10.3892/mco.2021.2457 Text en Copyright: © Maeda et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Maeda, Takaaki
Nishimura, Masato
Sogawa, Eishi
Kaji, Takashi
Irahara, Minoru
Iwasa, Takeshi
Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report
title Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report
title_full Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report
title_fullStr Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report
title_full_unstemmed Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report
title_short Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report
title_sort pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655730/
https://www.ncbi.nlm.nih.gov/pubmed/34909202
http://dx.doi.org/10.3892/mco.2021.2457
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