Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets

Extracellular vesicles and exomere nanoparticles are under intense investigation as sources of clinically relevant cargo. Here we report the discovery of a distinct extracellular nanoparticle, termed supermere. Supermeres are morphologically distinct from exomeres and display a markedly greater upta...

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Detalles Bibliográficos
Autores principales: Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Graves-Deal, Ramona, Trinh, Vincent Q., Ramirez, Marisol A., Sohn, Yoojin, Neininger, Abigail C., Taneja, Nilay, McKinley, Eliot T., Niitsu, Hiroaki, Cao, Zheng, Evans, Rachel, Glass, Sarah E., Ray, Kevin C., Fissell, William H., Hill, Salisha, Rose, Kristie Lindsey, Huh, Won Jae, Washington, Mary Kay, Ayers, Gregory Daniel, Burnette, Dylan T., Sharma, Shivani, Rome, Leonard H., Franklin, Jeffrey L., Lee, Youngmin A., Liu, Qi, Coffey, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656144/
https://www.ncbi.nlm.nih.gov/pubmed/34887515
http://dx.doi.org/10.1038/s41556-021-00805-8

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