Preliminary Pharmacogenomic-Based Predictive Models of Tamoxifen Response in Hormone-dependent Chilean Breast Cancer Patients

Tamoxifen (TAM), a selective oestrogen receptor modulator, is one of the most used treatments in oestrogen receptor-positive (ER+) early and metastatic breast cancer (BC) patients. The response to TAM has a high degree of inter-individual variability. This is mainly due to genetic variants in CYP2D6...

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Detalles Bibliográficos
Autores principales: Miranda, Carla, Galleguillos, Macarena, Torres, Roberto, Tardón, Karla, Cáceres, Dante D., Lee, Kuen, Redal, María A., Varela, Nelson M., Quiñones, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656167/
https://www.ncbi.nlm.nih.gov/pubmed/34899282
http://dx.doi.org/10.3389/fphar.2021.661443

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