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3D-QSAR, Molecular Docking, and MD Simulations of Anthraquinone Derivatives as PGAM1 Inhibitors

PGAM1 is overexpressed in a wide range of cancers, thereby promoting cancer cell proliferation and tumor growth, so it is gradually becoming an attractive target. Recently, a series of inhibitors with various structures targeting PGAM1 have been reported, particularly anthraquinone derivatives. In p...

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Detalles Bibliográficos
Autores principales:	Wang, Yuwei, Guo, Yifan, Qiang, Shaojia, Jin, Ruyi, Li, Zhi, Tang, Yuping, Leung, Elaine Lai Han, Guo, Hui, Yao, Xiaojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656170/ https://www.ncbi.nlm.nih.gov/pubmed/34899321 http://dx.doi.org/10.3389/fphar.2021.764351

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