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Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies
The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new vir...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656211/ https://www.ncbi.nlm.nih.gov/pubmed/34896650 http://dx.doi.org/10.1016/j.autrev.2021.103012 |
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author | Damoiseaux, Jan Dotan, Arad Fritzler, Marvin J. Bogdanos, Dimitrios P. Meroni, Pier Luigi Roggenbuck, Dirk Goldman, Michel Landegren, Nils Bastard, Paul Shoenfeld, Yehuda Conrad, Karsten |
author_facet | Damoiseaux, Jan Dotan, Arad Fritzler, Marvin J. Bogdanos, Dimitrios P. Meroni, Pier Luigi Roggenbuck, Dirk Goldman, Michel Landegren, Nils Bastard, Paul Shoenfeld, Yehuda Conrad, Karsten |
author_sort | Damoiseaux, Jan |
collection | PubMed |
description | The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Symposium on Autoantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting. |
format | Online Article Text |
id | pubmed-8656211 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Author(s). Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86562112021-12-09 Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies Damoiseaux, Jan Dotan, Arad Fritzler, Marvin J. Bogdanos, Dimitrios P. Meroni, Pier Luigi Roggenbuck, Dirk Goldman, Michel Landegren, Nils Bastard, Paul Shoenfeld, Yehuda Conrad, Karsten Autoimmun Rev Review The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Symposium on Autoantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting. The Author(s). Published by Elsevier B.V. 2022-03 2021-12-09 /pmc/articles/PMC8656211/ /pubmed/34896650 http://dx.doi.org/10.1016/j.autrev.2021.103012 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Damoiseaux, Jan Dotan, Arad Fritzler, Marvin J. Bogdanos, Dimitrios P. Meroni, Pier Luigi Roggenbuck, Dirk Goldman, Michel Landegren, Nils Bastard, Paul Shoenfeld, Yehuda Conrad, Karsten Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies |
title | Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies |
title_full | Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies |
title_fullStr | Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies |
title_full_unstemmed | Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies |
title_short | Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies |
title_sort | autoantibodies and sars-cov2 infection: the spectrum from association to clinical implication: report of the 15th dresden symposium on autoantibodies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656211/ https://www.ncbi.nlm.nih.gov/pubmed/34896650 http://dx.doi.org/10.1016/j.autrev.2021.103012 |
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