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Untargeted and Targeted Metabolomics Reveal the Underlying Mechanism of Aspirin Eugenol Ester Ameliorating Rat Hyperlipidemia via Inhibiting FXR to Induce CYP7A1

Hyperlipidemia is an important lipid disorder and a risk factor for health. Aspirin eugenol ester (AEE) is a novel synthetic compound which is made up of two chemical structural units from aspirin and eugenol. Therapeutic effect of AEE on hyperlipidemia has been confirmed in animal model. But the ac...

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Detalles Bibliográficos
Autores principales:	Xiao-Rong, Lu, Ning, Ma, Xi-Wang, Liu, Shi-Hong, Li, Zhe, Qin, Li-Xia, Bai, Ya-Jun, Yang, Jian-Yong, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656224/ https://www.ncbi.nlm.nih.gov/pubmed/34899293 http://dx.doi.org/10.3389/fphar.2021.733789

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