Stress Signal ULBP4, an NKG2D Ligand, Is Upregulated in Multiple Sclerosis and Shapes CD8(+) T-Cell Behaviors

BACKGROUND AND OBJECTIVES: We posit the involvement of the natural killer group 2D (NKG2D) pathway in multiple sclerosis (MS) pathology via the presence of specific NKG2D ligands (NKG2DLs). We aim to evaluate the expression of NKG2DLs in the CNS and CSF of patients with MS and to identify cellular s...

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Detalles Bibliográficos
Autores principales: Carmena Moratalla, Ana, Carpentier Solorio, Yves, Lemaitre, Florent, Farzam-kia, Negar, Levert, Annie, Zandee, Stephanie E.J., Lahav, Boaz, Guimond, Jean Victor, Haddad, Elie, Girard, Marc, Duquette, Pierre, Larochelle, Catherine, Prat, Alexandre, Arbour, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656234/
https://www.ncbi.nlm.nih.gov/pubmed/34873031
http://dx.doi.org/10.1212/NXI.0000000000001119

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