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miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury

Sepsis and acute lung injury (ALI) are linked to mitochondrial dysfunction; however, the underlying mechanism remains elusive. We previously reported that c-Jun N-terminal protein kinase 2 (JNK2) promotes stress-induced mitophagy by targeting small mitochondrial alternative reading frame (smARF) for...

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Detalles Bibliográficos
Autores principales:	Yang, Jing, Do-Umehara, Hanh Chi, Zhang, Qiao, Wang, Huashan, Hou, Changchun, Dong, Huali, Perez, Edith A., Sala, Marc A., Anekalla, Kishore R., Walter, James M., Liu, Shuwen, Wunderink, Richard G., Budinger, G.R. Scott, Liu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656235/ https://www.ncbi.nlm.nih.gov/pubmed/34899681 http://dx.doi.org/10.3389/fimmu.2021.700933

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