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TMAO promotes apoptosis and oxidative stress of pancreatic acinar cells by mediating IRE1α-XBP-1 pathway

BACKGROUND: Acute pancreatitis caused by hyperlipidemia is a severe life-threatening condition. Therefore, it is urgent to develop new therapeutic methods to treat this disease. METHODS: Cell viability was determined by the Cell Counting Kit-8 (CCK-8) assay. Western blotting (WB) was used to detect...

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Detalles Bibliográficos
Autores principales: Yang, Guodong, Zhang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656330/
https://www.ncbi.nlm.nih.gov/pubmed/34755714
http://dx.doi.org/10.4103/sjg.sjg_12_21