Cargando…

Divergent fates of antigen-specific CD8(+) T cell clones in mice with acute leukemia

The existence of a dysfunctional CD8(+) T cell state in cancer is well established. However, the degree to which CD8(+) T cell fates are influenced by the context in which they encounter cognate tumor antigen is less clear. We previously demonstrated that CD8(+) T cells reactive to a model leukemia...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xiufen, MacNabb, Brendan W., Flood, Blake, Blazar, Bruce R., Kline, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656370/
https://www.ncbi.nlm.nih.gov/pubmed/34758311
http://dx.doi.org/10.1016/j.celrep.2021.109991