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High BTLA Expression Likely Contributes to Contraction of the Regulatory T Cell Subset in Lupus Disease

B and T lymphocyte attenuator (BTLA) is a co-inhibitory receptor that is expressed by lymphoid cells and regulates the immune response. Consistent with an inhibitory role for BTLA, the disease is exacerbated in BTLA-deficient lupus mice. We recently demonstrated that the BTLA pathway is altered in C...

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Detalles Bibliográficos
Autores principales:	Aubergeon, Lucie, Sawaf, Matthieu, Felten, Renaud, Gottenberg, Jacques-Eric, Dumortier, Hélène, Monneaux, Fanny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656397/ https://www.ncbi.nlm.nih.gov/pubmed/34899718 http://dx.doi.org/10.3389/fimmu.2021.767099

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