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Longer Poly(U) Stretches in the 3′UTR Are Essential for Replication of the Hepatitis C Virus Genotype 4a Clone in in vitro and in vivo

The 3′ untranslated region (UTR) of the hepatitis C virus (HCV) genome plays a significant role in replication including the poly(U) tract (You and Rice, 2008). Here we established an HCV clone that is infectious in vitro and in vivo, from an Egyptian patient with chronic HCV infection and hepatocel...

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Detalles Bibliográficos
Autores principales:	Takagi, Asako, Amako, Yutaka, Yamane, Daisuke, Kitab, Bouchra, Tokunaga, Yuko, El-Gohary, Ahmed, Kohara, Michinori, Tsukiyama-Kohara, Kyoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656456/ https://www.ncbi.nlm.nih.gov/pubmed/34899647 http://dx.doi.org/10.3389/fmicb.2021.764816

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